Changes of Plasma Amino Acid and Inorganic Ion Concentrations with Maximum Exercises in Thoroughbred Young Horses

Hanzawa, Kei; Orihara, K.; Kubo, Katsuyoshi; Yamanobe, Akira; Hiraga, Atsushi; Watanabe, Shinji

doi:10.1294/jes1990.3.157

Cited by 8 publications

(7 citation statements)

References 15 publications

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“…The red blood cells are another source that may affect plasma AA levels. A genetic variation affecting free intracellular AA concentrations in erythrocytes of thoroughbreds has been reported to cause significant differences in post‐exercise AA plasma levels, especially for alanine, serine, threonine and lysine (Hanzawa et al., 1992). In our study we found post‐exercise values similar to those reported for basic AA negative horses which are the genetic variants with lower intracellular AA concentrations in erythrocytes.…”

Section: Discussionmentioning

confidence: 99%

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

Hackl

Hoven

Zickl

et al. 2009

Animal Physiology Nutrition

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The aim of this study was to investigate the effect of short intense exercise on plasma amino acid concentrations in trotters and to test the repeatability of plasma amino acids concentration in samples obtained on two independent days under field conditions. Plasma amino acid concentrations were analysed in blood samples of 36 standardbred trotters before and after intense exercise over a distance of 2000 m. Sampling was repeated in 20 horses after 35 days. Exercise intensity was estimated from post-exercise lactate levels. Horses were divided in two groups according to a cut-off lactate concentration at 15 mmol/l. The plasma concentrations of alanine, aspartate, glutamate, isoleucine, leucine, lysine and taurine increased and arginine, asparagine, citrulline, glutamine, glycine, histidine, methionine, serine, tryptophan and 3-methylhistidine decreased after exercise. Ornithine, threonine, tyrosine, phenylalanine and valine concentrations remained constant. Higher intensity of exercise significantly decreased tryptophan and increased taurine concentrations. Sampling day had a significant effect on the absolute pre- and post-exercise amino acid concentrations. Exercise had a significant influence on the concentrations of most plasma amino acids in trotters. These changes could reflect shifts between the free amino acid compartments, but there were also some indications for muscle catabolism. The amino acid supply of sporting horses could be of specific significance for maintaining muscle integrity and for the improvement of post-exercise recovery of competition horses.

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Section: Discussionmentioning

confidence: 99%

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

Hackl

Hoven

Zickl

et al. 2009

Animal Physiology Nutrition

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“…Osmotic fragility of the erythrocytes was determined by the haemolysis rate (HL, %) in a hypotonic salt solution (0.56%) with the equipment described earlier [8].…”

Section: Mchc and MCV Of The Washed Red Cells (Mchcrc And Mcvrc)mentioning

confidence: 99%

Effects of Exercise on Density and Osmotic Fragility of Circulating Red Cells in Normal and Splenectomized Thoroughbred Horses.

Hanzawa

Kubo

Kai

et al. 1999

JES

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“…Plasma Hp proved to be a useful indicator of infection/inflammation and haemolytic disease in the horse [6,9]. An increase in osmotic fragility of red cells and the plasma Hb concentration after exercise in Thoroughbred horses suggests the release of Hb from red cells into plasma by haemolysis based on acceleration of red cell membrane permeability [4]. Splenectomy significantly decreased the osmotic fragility of equine erythrocytes [2].…”

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confidence: 99%

Effects of Exercise on Plasma Haptoglobin Composition in Control and Splenectomized Thoroughbred Horses.

Hanzawa

Hiraga

Yoshida

et al. 2002

JES

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In splenectomized Thoroughbred horses (Group S), the plasma haptoglobin (Hp) concentration was increased by the operation but thereafter significantly decreased to a lower level than before the surgery. The red cell haemolysis rate in a hypotonic salt solution and haemoglobin (Hb) binding Hp after exercise in Group S were significantly lower than in control horses (Group C). These results suggest that: 1) the spleen accelerates the fragility of the red cell membrane; 2) osmotic sensitive red cells are easy to haemolyze during exercise; and 3) the haemolysis during exercise increases the Hb-binding Hp level in plasma and then accelerates the synthesis of Hp in liver. Therefore, plasma Hp is a clinical indicator of red cell membrane fragility and haemolysis in a blood vessel during exercise.

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Changes of Plasma Amino Acid and Inorganic Ion Concentrations with Maximum Exercises in Thoroughbred Young Horses

Cited by 8 publications

References 15 publications

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

The effects of short intensive exercise on plasma free amino acids in standardbred trotters

Effects of Exercise on Density and Osmotic Fragility of Circulating Red Cells in Normal and Splenectomized Thoroughbred Horses.

Effects of Exercise on Plasma Haptoglobin Composition in Control and Splenectomized Thoroughbred Horses.

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