Changes of epicardial fat thickness after laparoscopic sleeve gastrectomy: a prospective study

Salman, Ahmed; Salman, Mohamed Abdalla; Soliman, Ahmed; Youssef, A.A.; Labib, Safa; Helmy, Mona Youssry; Marie, Mohamed; Shawkat, Mohamed; Mostafa, Amir; Tourky, Mohamed; Sarhan, Mohamed D.; Qassem, Mohamed; Shaaban, Hossam El‐Din; Omar, M. M.; Abouelregal, Tarek Elsayed

doi:10.1080/07853890.2021.1903072

Cited by 9 publications

(4 citation statements)

References 27 publications

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“…Also important is proper hydration and ensuring good physical activity with the aerobic activity of medium intensity for 30-45 minutes most days (15). In agreement with these observations, prior retrospective research found a decrease in "epicardial fat thickness" after "bariatric surgery", which was related to "the degree of weight loss" (16). A similar conclusion was made by Gaborit et al (17) in a somewhat more latest study.…”

Section: Discussionsupporting

confidence: 66%

Epicardial Fat in Patients Undergo Laparoscopical-Sleeve Gastrectomy

Lolan¹,

Mahmood²,

Al-Gburi³

2022

Mil. Med. Sci. Lett.

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Introduction:Obesity is increasingly reported to be a contributing factor to vascular diseases resulting in increased patient morbidity and mortality rates leading to increase healthcare expenses. More precisely, the lipid deposition in cardiac tissues is interesting, due to their direct contribution to the disease initiation, prognosis, and all subsequent patients' fate. We do focus on the determination of the link between changes in body mass index (BMI) and epicardial fat deposition concerning gastric operation.Objective: The objective of this work was to study the relationship between weight reduction and "epicardial thickness" after laparoscopic-sleeve gastrectomy.Methods: Critically-ill patients were recruited from private clinics and out-patients hospital clinics. Forty-two patients undergoing laparoscopic-sleeve gastrectomy due to morbid obesity were included in this research. Patients followed for four months after the operation.Results: The results of this work find there is significant weight reduction in these patients in parallel with a reduction of epicardial fat thickness. Conclusion:Patients who experience laparoscopic-sleeve gastrectomy showed a reduction in weight in a parallel reduction in epicardial fat thickness.

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Section: Discussionsupporting

confidence: 66%

Epicardial Fat in Patients Undergo Laparoscopical-Sleeve Gastrectomy

Lolan¹,

Mahmood²,

Al-Gburi³

2022

Mil. Med. Sci. Lett.

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“…These alterations encompass an upsurge in the volume of epicardial adipose tissue and changes in the size and morphology of adipocytes (Iacobellis, 2021). Age-related metabolic adjustments, namely insulin resistance and modified lipid metabolism, can contribute to the expansion of epicardial adipose tissue (Salman et al, 2021). These shifts may impel a pro-inflammatory state within the adipose tissue, which could lead to the release of inflammatory mediators and an increased susceptibility to cardiovascular diseases, including atrial fibrillation (Guglielmi and Sbraccia, 2017).…”

Section: Age-related Changesmentioning

confidence: 99%

Understanding the impact of left atrial epicardial adipose tissue thickness on atrial fibrillation: A literature review

Fahimi,

Beikmohammadi

2024

AFRJMS

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Atrial Fibrillation (AF) is a common cardiac arrhythmia associated with significant morbidity and mortality. The role of Epicardial Adipose Tissue (EAT), particularly in the left atrium, has garnered attention in the pathophysiology of AF. This review aims to provide an overview of the association between the thickness of left atrial epicardial adipose tissue (LA-EAT) and the incidence of AF, while exploring the arrhythmogenic effects of LA-EAT and the impact of epicardial fat tissue changes with age and in pathological conditions. A comprehensive search of PubMed was conducted, and relevant studies were selected based on their inclusion criteria. The findings suggest that increased LA-EAT thickness is associated with an elevated risk of AF, potentially mediated through inflammatory and proarrhythmic effects. Age-related changes in epicardial fat tissue and alterations in pathological conditions, such as obesity, metabolic syndrome, and cardiovascular diseases, further contribute to the development and progression of AF. Further research is needed to deepen our understanding of these mechanisms and their clinical implications.

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“…Multiple studies have explored the effect of bariatric surgery, including sleeve gastrectomy and Roux‐en‐Y gastric bypass, on reducing EAT amount. 131 , 139 , 150 , 157 , 158 , 159 , 160 , 161 , 162 , 163 , 164 , 165 , 166 Most of them demonstrated a significant association between bariatric surgery and reduction in EAT amount; only one of these studies has reported a negative result (nonsignificant change in EAT amount), which might be due to a relatively shorter follow‐up duration (3 months). 162 According to a meta‐analysis, sleeve gastrectomy is more effective in decreasing EAT than Roux‐en‐Y gastric bypass.…”

Section: Exploration Of Targeting Eat As a Therapeutic Strategymentioning

confidence: 99%

Epicardial adipose tissue, metabolic disorders, and cardiovascular diseases: recent advances classified by research methodologies

Song,

Tan,

Deng

et al. 2023

MedComm

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Epicardial adipose tissue (EAT) is located between the myocardium and visceral pericardium. The unique anatomy and physiology of the EAT determines its great potential in locally influencing adjacent tissues such as the myocardium and coronary arteries. Classified by research methodologies, this study reviews the latest research progress on the role of EAT in cardiovascular diseases (CVDs), particularly in patients with metabolic disorders. Studies based on imaging techniques demonstrated that increased EAT amount in patients with metabolic disorders is associated with higher risk of CVDs and increased mortality. Then, in‐depth profiling studies indicate that remodeled EAT may serve as a local mediator of the deleterious effects of cardiometabolic conditions and plays a crucial role in CVDs. Further, in vitro coculture studies provided preliminary evidence that the paracrine effect of remodeled EAT on adjacent cardiomyocytes can promote the occurrence and progression of CVDs. Considering the important role of EAT in CVDs, targeting EAT might be a potential strategy to reduce cardiovascular risks. Several interventions have been proved effective in reducing EAT amount. Our review provides valuable insights of the relationship between EAT, metabolic disorders, and CVDs, as well as an overview of the methodological constructs of EAT‐related studies.

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Changes of epicardial fat thickness after laparoscopic sleeve gastrectomy: a prospective study

Cited by 9 publications

References 27 publications

Epicardial Fat in Patients Undergo Laparoscopical-Sleeve Gastrectomy

Epicardial Fat in Patients Undergo Laparoscopical-Sleeve Gastrectomy

Understanding the impact of left atrial epicardial adipose tissue thickness on atrial fibrillation: A literature review

Epicardial adipose tissue, metabolic disorders, and cardiovascular diseases: recent advances classified by research methodologies

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