Changes in selected subpopulations of lymphocytes in dogs infected with Babesia canis treated with imidocarb

Abstract

The presented results indicate that the resolution of clinical signs associated with babesiosis may be related to the stimulation and intensity of cellular immunity, dependent on the CD4+ T cells profile. After administration of imidocarb, the parasitemia is cleared which allows the recovery of the lymphocyte populations.

A flow cytometric assessment of the lymphocyte immunophenotypes in dogs naturally infected with Babesia rossi

“…At present, limited information of the host response against canine babesiosis is available. The Babesia parasite, more so after being damaged or inactivated by anti-babesial therapy, stimulates a rapid humoral response, which enhances the cellular immune response (24,25). Clinical resolution of canine babesiosis has been suggested to be associated with the stimulation and intensity of the CD4 + T lymphocyte driven cellular immunity (25).…”