Changes in plasma vitellogenin, sex steroids, calcitonin, and thyroid hormones related to sexual maturation in female brown trout (Salmo trutta)

Norberg, Birgitta; Björnsson, Björn Th.; Brown, Christopher L.; Wichardt, Ulf-Peter; Deftos, Leonard J.; Haux, Carl

doi:10.1016/0016-6480(89)90085-3

Cited by 96 publications

(71 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In fact, the plasma calcitonin level of female teleost increases in the reproductive period [38,41]. Using an in vitro assay system, we found that goldfish calcitonin suppressed osteoclastic activity in the goldfish scales [17].…”

Section: Discussionmentioning

confidence: 87%

See 1 more Smart Citation

Parathyroid hormone 1 (1–34) acts on the scales and involves calcium metabolism in goldfish

Suzuki

Danks

Maruyama

et al. 2011

Bone

View full text Add to dashboard Cite

The effect of fugu parathyroid hormone 1 (fugu PTH1) on osteoblasts and osteoclasts in teleosts was examined with an assay system using teleost scale and the following markers: alkaline phosphatase (ALP) for osteoblasts and tartrate-resistant acid phosphatase (TRAP) for osteoclasts. Synthetic fugu PTH1 (1-34) (100 pg/ml to 10 ng/ml) significantly increased ALP activity at 6 h of incubation. High-dose (10 ng/ml) fugu PTH1 significantly increased ALP activity even after 18 h of incubation. In the case of TRAP activity, fugu PTH1 did not change at 6 h of incubation, but fugu PTH1 (100 pg/ml to 10 ng/ml) significantly increased TRAP activity at 18 h. Similar results were obtained for human PTH (1-34), but there was an even greater response with fugu PTH1 than with human PTH. In vitro, we demonstrated that both the receptor activator of the NF-B ligand in osteoblasts and the receptor activator NF-B mRNA expression in osteoclasts increased significantly by fugu PTH1 treatment. In an in vivo experiment, fugu PTH1 induced hypercalcemia resulted from the increase of both osteoblastic and osteoclastic activities in the scale as well as the decrease of scale calcium contents after fugu PTH1 injection. In addition, an in vitro experiment with intramuscular autotransplanted scale indicated that the ratio of multinucleated osteoclasts/mononucleated osteoclasts in PTH-treated scales was significantly higher than that in the control scales. Thus, we concluded that PTH acts on osteoblasts and osteoclasts in the scales and regulates calcium metabolism in goldfish.3

show abstract

Section: Discussionmentioning

confidence: 87%

“…In the reproductive period of female teleosts, the plasma calcium level increases remarkably [36][37][38]. This calcium is bound to vitellogenin, which is a major component of egg protein and a calcium-binding protein [39,40].…”

Section: Discussionmentioning

confidence: 99%

Parathyroid hormone 1 (1–34) acts on the scales and involves calcium metabolism in goldfish

Suzuki

Danks

Maruyama

et al. 2011

Bone

View full text Add to dashboard Cite

show abstract

“…Thus, it may be speculated that the increased scale resorption observed in male and female salmonids during sexual maturation is mediated through the same receptor. In addition, plasma testosterone levels increase during sexual maturation of both male and female salmonids with peak values about 1 month before spawning (Scott and Sumpter, 1983;Olsson et al, 1987;Norberg et al, 1989), implying that the scale resorption observed in females during this phase can be affected by both E 2 and testosterone.…”

Section: Discussionmentioning

confidence: 99%

The Presence of High-Affinity, Low-Capacity Estradiol-17β Binding in Rainbow Trout Scale Indicates a Possible Endocrine Route for the Regulation of Scale Resorption

Persson

Shrimpton

McCormick³

et al. 2000

General and Comparative Endocrinology

View full text Add to dashboard Cite

High-affinity, low-capacity estradiol-17␤ (Etestosterone, but not by diethylstilbestrol. Hence, the ligand binding specificity is different from that of the previously characterized liver E 2 receptor, where E 2 is displaced by diethylstilbestrol, but not by testosterone. The putative scale E 2 receptor thus appears to bind both E 2 and testosterone, and it is proposed that the increased scale resorption observed during sexual maturation in both sexes of several salmonid species may be mediated by this receptor. No high-affinity, low-capacity E 2 binding could be detected in rainbow trout gill or skin.

show abstract

“…(B) The expression of GAPDH was used as a loading control. The experiments were performed three times in duplicate, and the values are (Deftos et al 1974, Watts et al 1975, Yamauchi et al 1976, 1978, Bjorsson et al 1986, Norberg et al 1989. The E 2 increases plasma CT levels in rainbow trout (Bjornsson et al 1986(Bjornsson et al , 1989) and a direct induction of estrogen on CT secretion from ultimobranchial glands in goldfish has also been suggested (Suzuki et al 2004).…”

Section: Discussionmentioning

confidence: 99%

Stimulation of salmon calcitonin on secretion of 17β-estradiol by the ovarian follicles of common carp, Cyprinus carpio

Paul

Mukherjee²,

Pramanick³

et al. 2007

Journal of Endocrinology

View full text Add to dashboard Cite

The effects of salmon calcitonin (sCT) on the secretion of 17b-estradiol (E 2 ) were examined in female common carp, Cyprinus carpio. Vitellogenic stage fish adapted to high-Ca water were i.p. injected with vehicle, sCT, human chorionic gonadotropin (hCG), or hCG plus sCT. To determine whether ovarian follicles are equipped with CT receptors, a CT binding assay was conducted. In the in vitro experiments, vitellogenic follicles were incubated with stimulators and inhibitors. Administration of sCT increased the basal and hCG-stimulated E 2 release in vivo and in vitro. Binding characteristics of [ 125 I]sCT to plasma membrane preparation of carp ovarian follicles showed saturability with high-affinity (K d Z48 . 48 pmol/l and B max Z1 . 2 pmol/mg protein). To clarify the mechanism of E 2 production by sCT, in vitro effect of sCT and hCG on aromatase activity (conversion of testosterone to E 2 ) and cytochrome P450 aromatase (P450arom) gene expression in carp ovarian follicles were investigated. Salmon CT-stimulated both aromatase activity and P450arom gene expression in ovarian follicles of carp. sCT-stimulated E 2 release by the ovarian follicles in vitro was augmented in the presence of dibutyryl cAMP. Inhibitor of protein kinase A (PKA), SQ 22536 inhibited sCT-stimulated steroid production in a dose-dependent manner. Specific inhibitor of protein kinase C (PKC), NPC-15437 dihydrochloride had no inhibitory effects on sCT-induced E 2 release. The present study indicates that sCT binds specifically to carp ovary and stimulates E 2 production by increasing the activity of cytochrome P450 aromatase and P450arom gene expression. The results further suggest that stimulatory action of sCTon E 2 production is mediated through cAMP pathway.

show abstract

Changes in plasma vitellogenin, sex steroids, calcitonin, and thyroid hormones related to sexual maturation in female brown trout (Salmo trutta)

Cited by 96 publications

References 43 publications

Parathyroid hormone 1 (1–34) acts on the scales and involves calcium metabolism in goldfish

Parathyroid hormone 1 (1–34) acts on the scales and involves calcium metabolism in goldfish

The Presence of High-Affinity, Low-Capacity Estradiol-17β Binding in Rainbow Trout Scale Indicates a Possible Endocrine Route for the Regulation of Scale Resorption

Stimulation of salmon calcitonin on secretion of 17β-estradiol by the ovarian follicles of common carp, Cyprinus carpio

Contact Info

Product

Resources

About