Changes in hematological biomarkers of Nellore cows at different reproductive stages

Abstract

This study was conducted to evaluate changes in hematological biomarkers of Nellore cows at different reproductive stages. Fifteen multiparous cows with 4 ± 1 years of age and live weight of 400 ± 50 kg were used at different stages (non-pregnant, in the initial, middle and late pregnancy, at birth, one day postpartum, 30 and 60 days postpartum). Blood collections were performed every 30 days and assayed for the following hematological biomarkers: hemogram (red blood cells, globular volume, hemoglobin, mean corpuscular volume (MCV) and mean corpuscular hemoglobin concentration (MCHC)) and leukogram (total and differential counts). The erythrogram was influenced (p < 0.001) by the reproductive stages, with variation in the results obtained for the total red cell count, hemoglobin content, globular volume, MCV, MCHC and total plasma proteins. The reproductive stages influenced the leukocyte profile with variation in the total leukocyte count and in the absolute values of neutrophils, eosinophils, lymphocytes and monocytes. Hematological biomarkers of Nellore cows showed significant changes due to the physiological adjustments required in response to the metabolic requirements imposed in the final stage of pregnancy and in the beginning of lactation, ensuring the nutritional contribution in energy and oxygen transported through the blood.

Pengaruh Bunting dan Laktasi Terhadap Hematologi dan Mineral Kambing Peranakan Ettawa di Kulonprogo, Yogyakarta, Indonesia

“…Keseluruhan rata-rata leukosit hasil penelitian ini masuk dalam referensi normal sebesar 4,00-13,00 ribu/µL (Byers &Kramer, 2010), juga sesuai dengan leukosit pada kambing Omani sebesar 14,6±3,32 ribu/µL, kambing Barbari sebesar 12,88±4,83 ribu/µL, kambing Black Aardi sebesar 12,20±2,97 ribu/µL, dan kambing Damascus sebesar 8,05±2,06 ribu/µL (Al-Bulushi et al, 2017). Rata-rata leukosit tidak berbeda antara kambing bunting dan laktasi (p>0,05), sesuai dengan leukosit pada kambing bunting dan laktasi Nguni, Boer dan Non-descript di Afrika Selatan (Idamokoro et al, 2018), domba Santa Inês bunting dan laktasi serta domba Morada Nova pada akhir kebuntingan dan postpartum (Bezerra et al, 2017), sapi bunting pada trisemester dan seminggu awal laktasi di Zaria (Ate, 2006), serta sapi Nellore bunting dan laktasi (De Oliveira et al, 2019). Hasil ini menunjukkan bahwa antara kambing bunting dan laktasi tidak ditemukan indikasi keradangan, ataupun respon stres yang memicu hormon kelenjar adrenal dalam sistem sirkulasi dalam menstimulasi peningkatan leukosit.…”

Neutrophil and Lymphocyte (N/L) Ratio of Gestation and LactationSaperaGoats at Kambing Farm, Sukoharjo, Ngaglik, Sleman

“…These results indicate that pregnancy and lactation have an effect on the N/L ratio in Sapera goats. According to Palacios [7] and Oliveira [6] , there are differences in the hematological and leukogram images between pregnant and lactating goats. Lymphocyte value will be higher in the gestation period, while the neutrophil value is higher in the lactation period [12,13] .…”

Effect of parity on metabolic and oxidative stress profiles in Holstein dairy cows

“…Changes in total leucocyte count and differential leucocyte count could be attributed to stress with consequent release of cortisol in the blood stream, which, in turn, increases the number of leukocytes in circulation [ 53 ]. Lymphocyte decrease at the final stage of gestation is associated with production of large amounts of adrenocorticoids in both the cow and the fetus [ 54 ]. Several factors in reducing leukocyte count in late pregnancy have been identified, for example, diet, hormonal level, and managemental strategies [ 55 ].…”