Changes in heavy metal levels, reproductive characteristics, oxidative stress markers and testicular apoptosis in rams raised around thermal power plant

Akarsu, Serkan Ali; Türk, Gaffari; Arkalı, Gözde; Çeribaşı, Ali Osman; Yüce, Abdurrauf

doi:10.1016/j.theriogenology.2021.12.004

Cited by 5 publications

(4 citation statements)

References 75 publications

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“…Heavy metal pollution has significant adverse effects on the reproductive functions of both animals and humans [36][37][38]. Humans and animals are acutely or chronically exposed to heavy metals through food and water intake [39].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Effects of thymoquinone against D- galactose and aluminum chloride induced testicular dysfunction in rats.

AKARSU,

ÇETİN

2023

Türk Doğa Ve Fen Dergisi

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Alzheimer's disease affects all tissues negatively. In this study, it was aimed to determine the effects of TQ on testicular toxicity in rats with experimental Alzheimer's disease. In the study, 33 Wistar Albino rats weighing 190-230 gr were used. Rats were 11 rats in each group; were divided into 3 equal groups as control, ALZ and ALZ+TQ. The control group was given saline by IP route for 28 days daily. The ALZ group was given 60 mg/kg D-gal + 40 mg/kg AlCl3 IP for 28 days daily. The ALZ+TQ group was given 60 mg/kg D-gal + 40mg/kg AlCl3 for 28 days by IP + 20 mg/kg TQ by oral gavage for last 14 days daily. According to the findings of our study, a decrease in SOD, CAT, GPx activity and GSH levels and an increase in MDA levels were determined in the ALZ group. In the ALZ+TQ group, while SOD, GPx, CAT activities and GSH levels increased, MDA levels decreased. Semen analyzes showed that there was a decrease in sperm motility and sperm density in the ALZ group, and an increase in the rate of abnormal sperm and dead spermatozoa. In the ALZ+TQ group, sperm motility, abnormal sperm rate and dead spermatozon rate improved. As a result, it was determined that the decrease in semen quality and increase in oxidative stress induced by AlCl3+D-Gal were suppressed by TQ, protecting the testicular tissue from oxidative damage and increasing semen quality.

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Section: Discussionmentioning

confidence: 99%

“…Environmental pollution adversely affects the structural and physiological integrity of the testicles and may cause infertility [36,50]. Testicular oxidative stress is one of the main factors causing infertility [51].…”

Section: Discussionmentioning

confidence: 99%

Effects of thymoquinone against D- galactose and aluminum chloride induced testicular dysfunction in rats.

AKARSU,

ÇETİN

2023

Türk Doğa Ve Fen Dergisi

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“…Demirak et al ( 2006 ) stated that the heavy metals (Cd, Cr, Pb, Zn, and Cu) which were found in the tissues of carps may have resulted from Yatağan CFPP. In Elbistan plain, around the Afşin-Elbistan CFPP area, Akarsu et al ( 2022 ) investigated rams for changes in heavy metal levels in their blood serum and testicular tissues and to evaluate their effect on reproductivity. CFPP was found to be an important factor for the heavy metal pollution in the soil in its vicinity, and rams were thus negatively affected.…”

Section: Environmental Effects Of Coal-fired Power Plantsmentioning

confidence: 99%

Impacts of coal-fired power plants for energy generation on environment and future implications of energy policy for Turkey

Vardar

Demirel

Onay

2022

Environ Sci Pollut Res

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Turkish government aimed to increase the installed capacities of coal-fired power plants (CFPPs) according to several policies and strategic plans published in recent years. Energy production from CFPPs and subsidizing the coal sector were selected for reducing the import dependency as a cheaper option. CFPPs with gaseous emissions as well as fly ash and fine dust, along with ash storage, coal storage, and coal mining operations and water use for cooling of the plants, affect the environmental quality. Hence, the health of inhabitants of the environment is affected. CFPPs to be built, according to strategic plans, will emit a significant amount of greenhouse gases (GHGs) and would severely undermine the targets for a 1.5 ℃ or 2 ℃ warmer world. Subsidies to the coal sector, along with exemptions from environmental regulations, combined with slower growth of energy production from renewable energy sources (RES), may lead to a path dependence on coal, while the rest of the world increases their energy production from RES. This study demonstrates the concrete examples of pollution caused by CFPPs in Turkey, along with health effects with the addition of policy context toward utilization of CFPPs, to point out the risks these plants constitute both for the environment and economy. Increasing the share of RES in the energy mixture is particularly important for Turkey due to being in a geographical region that is highly vulnerable to climate change effects. This study also briefly discusses how the increase of RES and de-carbonization in Turkey could be conducted in the short- and long-term, upon the literature provided.

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“…10 Kontaminasi logam pada makanan merupakan masalah serius karena logam berat bersifat racun meskipun pada konsentrasi rendah sehingga dapat berdampak pada kesehatan masyarakat, 11 terutama pada logam non-essensial seperti Pb, Cd, Cr, dll yang tidak diperlukan tubuh. 12 Akumulasi logam berat pada tubuh manusia dapat menjadi risiko terjadinya berbagai penyakit seperti kanker paru-paru 13 , kanker tiroid 14 , berbagai penyakit kardiovaskuler 15, kanker lambung dan kerongkongan 16 , kanker payudara 17 , kanker prostat 18 , dan penyakit-penyakit lainnya.…”

Section: Pendahuluanunclassified

Logam Berat dan Probabilistik Penilaian Risiko Kesehatan Melalui Konsumsi Beras dari Lahan Sawah di Hulu Sungai Citarum

Handayani¹,

Sukarjo²,

Dewi³

et al. 2022

Jurnal Kesehatan Lingkungan Indonesia

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Latar belakang: Beras merupakan salah satu makanan pokok masyarakat Indonesia sehingga perlu adanya jaminan keamanan pada beras khususnya bebas dari cemaran logam berat. Penelitian ini bertujuan untuk mengetahui kandungan konsentrasi logam berat pada beras yang ditanam pada lahan pertanian di Kabupaten Bandung dan menganalisis risiko kesehatan masyarakat yang mengkonsumsi beras tersebut.Metode: penentuan lokasi pengambilan contoh dilakukan dengan metode purposive sampling pada lahan pertanian yang siap panen di beberapa kecamatan di Kabupaten Bandung dengan jumlah contoh beras sebanyak 26 sampel. Analisis logam berat yang dilakukan adalah analisis logam berat Pb, Cd, Cr, Ni, Co, Cu dan Zn dengan ekstrak HNO3:HClO4 dan diukur menggunakan Atomic Absorbption Spectrophotometer (AAS). Analisis probabilistik penilaian risiko kesehatan masyarakat dilakukan dengan menganalisis nilai estimated daily intake (EDI), estimated weekly intake (EWI), risiko non-karsinogenik dan risiko karsinogenik. Hasil: semua contoh beras mengandung logam berat Cr, Co, Cu dan Zn dengan nilai konsentrasi berturut-turut berkisar antara 0.64-2.28 mgkg-1, 1.18-2.66 mgkg-1, 0.64-3.47 mgkg-1 dan 5.44-8.69 mgkg-1. Konsentrasi logam Cu pada contoh beras yang diambil pada lahan pertanian kawasan industri berbeda nyata dengan contoh beras di luar kawasan industri dengan nilai p sebesar 0.014. Risiko non-karsinogenik yang ditimbulkan jika mengkonsumsi beras dari lahan pertanian Kabupaten Bandung tidak mungkin untuk terjadi karena nilai hazard index (HI) menunjukkan angka <1, nilai HI secara berurutan yaitu anak-anak (0.0880)>remaja (0.0370)>dewasa (0.0259)>manula (0.0281) dan risiko karsinogenik juga menunjukkan nilai yang dapat ditoleransi karena di bawah 10-4 untuk semua katogeri umur (anak-anak, remaja, dewasa, manula) dengan nilai cancer risk (CR) berturut-turut sebesar 6.15x10-7, 6.72x10-7, 2.53x10-6 dan 2.74x10-6.Simpulan: beras yang dihasilkan dari lahan pertanian di Kabupaten Bandung aman untuk dikonsumsi oleh masyarakat karena risiko kesehatan yang ditimbulkan masih dapat ditoleransi ABSTRACTTitle: Heavy Metals and Probabilistic Risk Assessment Via Rice Consumption From Rice Fields in Upstream of The Citarum River Background: Rice is one of the staple foods of the Indonesian people, so it is necessary to guarantee the safety of rice, especially free from heavy metal contamination. This study aims to determine the concentration of heavy metals in rice grown on agricultural land in Bandung Regency and analyze the health risks of the people who consume the rice. Method: the determination of location of sampling was carried out by purposive sampling method on agricultural land that was ready for harvest in several sub-districts in Bandung Regency with a total of 26 samples of rice. Heavy metal analysis carried out was heavy metal analysis of Pb, Cd, Cr, Ni, Co, Cu and Zn with HNO3:HClO4 extract and measured using Atomic Absorption Spectrophotometer (AAS). Probabilistic analysis of public health risk assessment was carried out by analyzing the estimated daily intake (EDI), estimated weekly intake (EWI), non-carcinogenic risk and carcinogenic risk.Results: all rice samples contained Cr, Co, Cu and Zn metals with concentration values ranging from 0.64-2.28 mgkg-1, 1.18-2.66 mgkg-1, 0.64-3.47 mgkg-1 and 5.44-8.69 mgkg-1, respectively. The concentration of Cu metal in rice samples taken on agricultural land in industrial areas was significantly different from rice samples outside industrial areas with a p value of 0.01. The non-carcinogenic risk caused by consuming rice from agricultural land in Bandung Regency is unlikely to occur because the hazard index (HI) value shows the number <1, the HI values are children (0.0880)>adolescents (0.0370)>adults (0.0259 )> the elderly (0.0281) and the carcinogenic risk also shows a value that can be tolerated because it was below 10-4 for all age categories (children, adolescents, adults and the elderly) with a cancer risk (CR) value of 6.15x10-7, 6.72x10-7, 2.53x10-6 and 2.74x10-6.Conclution: Rice produced from agricultural land in Bandung Regency is safe for consumption by the community because the health risks caused are still tolerable.

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Changes in heavy metal levels, reproductive characteristics, oxidative stress markers and testicular apoptosis in rams raised around thermal power plant

Cited by 5 publications

References 75 publications

Effects of thymoquinone against D- galactose and aluminum chloride induced testicular dysfunction in rats.

Effects of thymoquinone against D- galactose and aluminum chloride induced testicular dysfunction in rats.

Impacts of coal-fired power plants for energy generation on environment and future implications of energy policy for Turkey

Logam Berat dan Probabilistik Penilaian Risiko Kesehatan Melalui Konsumsi Beras dari Lahan Sawah di Hulu Sungai Citarum

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