Changes in antioxidant defense status in hypercholesterolemic rats treated with Ajuga iva

Effect of Diet Supplemented with Quinoa Seeds on Oxidative Status in Plasma and Selected Tissues of High Fructose-Fed Rats

“…The other studies [14,15] have also shown that during oxidative stress, the addition of some plants rich in antioxidants compounds could improve activities of free radical scavenging enzymes. Bouderbala et al [12] observed similar changes in activity of both aforementioned enzymes in hearts, after Ajuga iva treatment, which enhanced GPX activity in hypercholesterolemic rats in comparison with the untreated group, but this plant did not influence CAT activity in this organ. Increasing the activity of enzymatic antioxidants demonstrate that quinoa seeds added to rats fodder can protect heart against free radicals attack leading to oxidative damage.…”

“…Quinoa seeds showed decreasing effect on the eSOD activity, in contrary to vitamin E and another antioxidant compounds, which caused increase of SOD activity [11,12]. Perhaps, significant decrease in SOD activity could be associated with high content of methionine in quinoa seeds compared to normal diet [13].…”

Naturally Occurring Iridoids and Secoiridoids. An Updated Review, Part 4

“…84) The aqueous extract of the Algerian plant, Ajuga iva was able to reduce the oxidative stress in hypercholesterolemic (HC) rats by increasing the antioxidant enzymes activity. 92) The butanol fraction of the lyophilized aqueous extract of A. iva contained iridoids with 8-O-acetylharpagide (165) as major constituent. This fraction at different doses (5, 10 or 15 mg/kg body weight) was able to reduce oxidative stress in HC rats on interperitoneal injection for 15 d by increasing the activities of antioxidant enzymes.…”

Bioactive properties of medicinal plants from the Algerian flora: Selecting the species with the highest potential in view of application purposes

“…Regarding gastric disorders and spasms, Saccocalyx satureioides (Ozenda, 2004), Asteriscus graveolens (Bellakhdar, 1997) and Limoniastrum guyonianum (Chaieb and Boukhris, 1998) infusions have been applied. A. iva infusion is also used for its alleged hypolipidemic and hypocholesterolemic effects Bouderbala et al, 2008), while the infusion of Herniaria hirsuta is used as a remedy for urinary and kidney problems (Atmani et al, 2004), just to give a few examples. Nevertheless, scientific studies are required in order to validate all those claimed effects.…”