Changes in anticholinesterase, antioxidant activities and related bioactive compounds of carob pulp (Ceratonia siliqua L.) during ripening stages

Continuous and pulsed ultrasound-assisted extraction of carob’s antioxidants: Processing parameters optimization and identification of polyphenolic composition

“…Based on the results, immature carobs should be preferred, as they are more enriched in polyphenols and are likely to exhibit stronger antioxidant, anti-inflammatory, antidiabetic, cardioprotective, and anticancer effects. The observed progressive pattern was in agreement with the findings reported by Benchikh et al (2014), Ouzounidou et al (2012), and Saci et al (2020), who also mentioned that polyphenolic content of carobs declined gradually with ripening, revealing significant loss rates ranging from 83 to 93% [37] , [38] , [39] , [40] .…”

“…This makes the quantitative comparison of results from different studies a very difficult task. The TPC recorded, in this study, for the unripe carob pulp was markedly higher than those reported by Sebai et al (2013) (28.07 ± 0.99 mg GAE/kg carob pulp) and Qasem et al (2018) (127.02 ± 7.18 mg GAE/g dry extract) for extracts of immature carobs, but, at the same time, lower than those found by Benchikh et al (2014) (19.82 ± 0.48 g GAE/100 g carob dry weight) and Saci et al (2020) (258.55 ± 2.57 mg GAE/g dry matter) [37] , [38] , [41] , [42] . More recently, Ydjedd et al (2017) reported the content of 162.55 ± 5.44 mg GAE/g dry extract for immature carobs grown in Algeria, a value that is closed to the one reported in the present study [43] .…”

“…During ripening, a series of complex biochemical reactions occur, including degradation or synthesis and accumulation of bioactive components. Thus, the levels of health-related phytochemicals are affected, and this, in turn, leads to the development of the final characteristics of the mature fruit [37] , [38] . In the present study, it was proven that the ripening process has a remarkable effect on polyphenolic composition.…”

In-vitro antiproliferative efficacy of Abrus precatorius seed extracts on cervical carcinoma

“…Another study reported that polarity of the solvents used for extraction plays an important role in the concentration of phenols and flavonoids 24 – 26 . Indeed, several factors, such as the type of solvent, the extraction process, the part of the plant, temperature, and so on, might influence the yield and extraction of phenolic compounds 27 , 28 .…”

Investigation of Photoprotective, Anti-Inflammatory, Antioxidant Capacities and LC–ESI–MS Phenolic Profile of Astragalus gombiformis Pomel

“…The TS content islow compared to that of phenolic compounds (2.97 mg Quillaja/g DM). Several factors have been reported to influence the TPC of plants, including geographical origin [42], environmental and ecological conditions [43], variety and degree of maturation [44], and finally extraction conditions [45,46].…”