Introduction:To understand how age and other factors impacted outcomes, we examined characteristics of patients aged 65 years and older hospitalized with COVID-19. Material and methods: This was a retrospective cohort study that included all patients aged 65 years and older with laboratory-confirmed COVID-19, who were admitted to a suburban New York academic medical centre between 15 March and 13 May 2020, and discharged. Results: Of 196 patients, the median age was 76 years, with 57% male, and 66% white. A greater proportion of "older" (77-105 years) compared to "old" (65-76 years) patients were admitted with a primary diagnosis other than COVID-19 (34% vs. 15%), were afebrile (80% vs. 67%), and had a clear initial chest X-ray (19% vs. 8%). Older patients had a higher prevalence of dementia (26% vs. 1.0%), cardiac (42% vs. 28%), and vascular disease (20% vs. 9%). Overall survival was lower among older compared to old patients (55% vs. 74%, p = 0.026) and when mechanical ventilation (20% vs. 46%, p = 0.29) or vasopressors (15% vs. 41%, p = 0.46) were required (20% vs. 46%, p = 0.029) and when new hepatic dysfunction (24% vs. 65%, p < 0.001) or new renal failure (29% vs. 56%, p = 0.015) developed. Factors at presentation that were associated with significantly lower survival included hypoxaemia, elevation of total white blood cell count, procalcitonin, and d-dimer. Conclusions: Overall mortality was 34%. Survival was 2-to 3-fold higher for those aged 65-76 years compared to those aged 77 years and older who required advanced therapies such as mechanical ventilation. Improving clinical parameters were associated with significantly higher survival, regardless of age.