Challenges of monitoring global diabetes prevalence

Ezzati, Majid; Zeng, Bin; Riley, Leanne M; Stevens, Gretchen A; Hajifathalian, Kaveh; Danaei, Goodarz

doi:10.1016/s2213-8587(17)30036-0

Cited by 4 publications

(3 citation statements)

References 8 publications

(5 reference statements)

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“…5 The disease progresses silently, worsens and leads to irreversible damages. 6,7 Mechanism of disease often associates with changes in the structure and function of renal cells due to the effects of prolonged hyperglycemia, the activation of metabolic mechanisms associated with redox imbalance and inflammatory response. 8 On the other hand, the kidney injuries have been affected partly by race, ethnicity and socioeconomic status.…”

Section: Introductionmentioning

confidence: 99%

<p>Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus</p>

Quang¹,

Nguyet²,

Thao³

et al. 2020

DMSO

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The purpose of this study was evaluating the early diagnostic value of two specific tubular markers neutrophil gelatinase-associated lipocalin (NGAL) and kidney injury molecule-1 (KIM-1) in diabetes nephropathy. Patients and Methods: Cross-sectional study was carried in three groups of patients from 10/2017 to 10/2018 in Military Hospital 103. Group I included 30 healthy peoples with estimated glomerular filtration rate (eGFR) >60 mL/min/1.73 m 2 and urine albumin creatinine ratio (uACR) <30 mg/g. Group II included 30 type 2 diabetic patients having uACR <30 mg/g, eGFR >60 mL/min/1.73 m 2. Group III included 30 type 2 diabetic patients having uACR >30 mg/g, eGFR >60 mL/min/1.73 m 2. Results: Urine KIM-1 and NGAL increased progressively from control group (57.29 ± 25.91 pg/mL; 25.71 ± 13.69 ng/mL) to the group of diabetic patients with uACR <30 mg/g (167.06 ± 44.01 pg/mL; 37.42 ± 10.89 ng/mL) and the group of diabetic patients with uACR ≥30 mg/g) (p < 0.05). There were moderate correlations between KIM-1 (r = 0.48, p < 0.05) and NGAL (r = 0.45, p < 0.05) with uACR. There was a mild correlation between KIM-1 and NGAL (r = 0.29, p < 0.05). KIM-1 and NGAL are the independent tests to detect diabetic nephropathy. The sensivity and specificity of KIM-1 with cutoff value of 174.95 pg/mL were 62.37% and 73.48%, respectively; the sensivity and specificity of NGAL with cutoff value of 35.2 ng/mL were 60.45% and 70.37%, respectively. Conclusion: KIM-1 and NGAL in urine are independent markers for early diagnostic diabetic nephropathy.

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Section: Introductionmentioning

confidence: 99%

<p>Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus</p>

Quang¹,

Nguyet²,

Thao³

et al. 2020

DMSO

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“…Earlier, the prevalence of hypertension in men was reported to be high and it was largely attributed to the nature of their jobs. 5 But, with the passage of time, the trend seems to be changing. According to a report, more than 25% of the female adult world population is hypertensive.…”

Section: Introductionmentioning

confidence: 99%

A study on the prevalence and awareness of hypertension among women in the reproductive age group and the factors contributing to it in a rural area of Jorhat district, Assam

Singh¹,

Rahman²

2017

Int J Community Med Public Health

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Background: Hypertension has been identified as one of the major causes of morbidity and mortality in both developed and developing nations. Prevalence is seen to be increasing in the rural areas, especially among the females in the reproductive age group. The prevalence of hypertension is found to be high in Assam, while the awareness is quite low thus necessitating a study in this regard.Methods: A total of 400 women in the reproductive age group were selected from Bagchung block, Jorhat by Simple Random Sampling. They were interviewed and their blood pressure was measured along with some anthropometric variables. Classification of hypertension was done as per the US Seventh Joint National Committee (JNC 7) report on the prevention, evaluation and treatment of high BP.Results: A total of 23.5% prevalence of hypertension was found among the study subjects. 44.5% of the total was in the pre hypertensive stage. 77% of them had heard of hypertension while only 20% were aware of its side effects. Extra salt intake, family history and underlying medical conditions were the major risk factors.Conclusions: Knowledge, awareness on hypertension in women in this part of the district is poor and the prevalence is high and their life style practices are grossly contributing to it. Therefore, efforts should be geared towards improving the levels of awareness of the women regarding hypertension and the risk factors.

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“…Since diabetic patients constitute a significant percentage of the population, it is advantageous to provide a USN to monitor their conditions in real time and to evaluate the global epidemiology of the disease. [26][27][28] A smart sensors network could be used to optimize insulin administration, possibly under remote control by a doctor, or to provide emergency hospitalization in case of emergency. 29,30 Glucose sensors may also be combined with other sensors to provide a more complete monitoring coverage.…”

mentioning

confidence: 99%

Low Cost Inkjet Fabrication of Glucose Electrochemical Sensors Based on Copper Oxide

Bernasconi

Mangogna

Magagnin

2018

J. Electrochem. Soc.

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The availability of low cost, efficient and wearable glucose sensors is one of the prerequisites for the development of ubiquitous sensors networks for the efficient monitoring of diabetes epidemiology. Starting from this principle, wet metallization and low cost inkjet printing were employed in the present work to manufacture non-enzymatic electrochemical sensors. CuO nanoparticles were inkjet printed on platinum, which was electrodeposited on stainless steel. The active layer obtained in this way showed an acceptable linear range for glucose detection and a good sensitivity when used as sensor. The influence on performances of interfering species and curvature were investigated, demonstrating a negligible effect for the first and a decrease in linearity of the response and sensitivity for the latter.

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Challenges of monitoring global diabetes prevalence

Cited by 4 publications

References 8 publications

<p>Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus</p>

<p>Evaluation of Urinary Neutrophil Gelatinase Associated Lipocalin and Kidney Injury Molecule-1 as Diagnostic Markers for Early Nephropathy in Patients with Type 2 Diabetes Mellitus</p>

A study on the prevalence and awareness of hypertension among women in the reproductive age group and the factors contributing to it in a rural area of Jorhat district, Assam

Low Cost Inkjet Fabrication of Glucose Electrochemical Sensors Based on Copper Oxide

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