Challenges in Systematic Reviews of Complementary and Alternative Medicine Topics

Shekelle, Paul G; Morton, Sally C.; Suttorp, Marika J; Buscemi, Nina; Friesen, Carol

doi:10.7326/0003-4819-142-12_part_2-200506211-00003

Cited by 71 publications

(59 citation statements)

References 33 publications

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“…Although many herbal medicines have a long tradition in the management of various liver diseases in Asia, the lack of scientific evidence regarding their efficacy or safety has become a medical issue (Shekelle et al, 2005;Stickel et al, 2001). Several herbal drugs have been evaluated for their hepatotherapeutic effects and underlying mechanisms, especially via antioxidant properties (Kim et al, 2009;Shaker et al, 2010).…”

Section: Resultsmentioning

confidence: 99%

Hepatoprotective effect ofAmomum xanthoidesagainst dimethylnitrosamine-induced sub-chronic liver injury in a rat model

Wang

Choi

et al. 2013

Pharmaceutical Biology

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Son (2013) Hepatoprotective effect of Amomumxanthoides against dimethylnitrosamine-induced sub-chronic liver injury in a rat model, Pharmaceutical Biology, 51:7, 930-935, DOI: 10.3109/13880209.2013 and 100 mg/kg) was given once a day for 3 weeks. Results and conclusion: WAX (100 mg/kg) significantly attenuated the DMN-induced excessive release of alanine aminotransferase (123.6 IU/L), aspartate aminotransferase (227.9 IU/L), alkaline phosphatase (820.9 IU/L) and total bilirubin (0.50 g/dL) in serum (p50

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Section: Resultsmentioning

confidence: 99%

Hepatoprotective effect ofAmomum xanthoidesagainst dimethylnitrosamine-induced sub-chronic liver injury in a rat model

Wang

Choi

et al. 2013

Pharmaceutical Biology

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“…53 Natural Medicines Comprehensive Database, 54 AcuTrials 59 and Google Scholar will be searched. 52,55 The bibliographies of published papers and cluster searching of key authors will also be used to identify additional evidence for inclusion in the review. A preliminary outline of the search terms can be found in the Additional File 1.…”

Section: Search and Selection Methodsmentioning

confidence: 99%

“…no new themes or information are identified) and there is adequate information to answer the research questions and justify the selection of up to 20 and Google Scholar will be searched. 52,55 Bibliographies of published papers, and cluster searching of key authors will additionally inform the iterative process. Key words for the first search will focus on the utilization of T&CM and will be based on three categories 1) diabetes and 2) palliative and end of life care and 3) common comorbidities, conditions or problems (Table 2).…”

Section: Search Strategymentioning

confidence: 99%

Protocol for a Rapid Evidence Review of Traditional and Complementary Medicine for People with Diabetes Receiving Palliative or End-of-Life Care

Hunter¹,

Arentz²,

Deed³

2017

HPMIJ

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Abbreviations: T&CM, traditional and complementary medicine;PICO, patient/population/problem, intervention, comparison, outcome; UK, united kingdom; USA, united states of America; SR, systematic reviews; AMED, allied and complementary medicine database IntroductionThis paper presents a protocol using rapid review methods that will be used to select a limited number of traditional and complementary medicine (T&CM) interventions and evaluate the available evidence. The results from this review will be used to inform an update of the Australian Guidelines for Managing Diabetes at the end of life (Guidelines). Rapid review methods were chosen to maximise the number of T&CM interventions and different problems that could realistically be reviewed in a timely manner given the resources available to the research team.Rapid review methods are increasingly used as an alternative to systematic reviews (SR) when there are time, resource or other logistical constraints.1-5 Estimated costs of a comprehensive SR exceed USD$100,000 with an average of 1,139 hours to complete. 6For many research teams, pragmatic decisions must be made that may compromise the accepted 'gold standard' systematic review methods used to minimise bias, which in turn impacts the validity and generalisability of the results. As such, a rapid review is not a replacement for a full systematic review and meta-analysis. Notwithstanding methodological constraints, rapid reviews should endeavour to be transparent, systematic and reproducible. 4 Most Rapid Reviews do not publish a protocol.3 However, the recent establishment of a Cochrane Rapid Reviews Methods Group highlights the need to develop methods that minimise bias despite project constraints. Outlining the objectives and methodology a priori will further improve the transparency and quality of the methods used to frame the review questions, help reduce bias arising from the rapid review study design, and enhance the reproducibility of the results. AbstractBackground: Rapid review methods are increasingly used as an alternative to systematic reviews when there is time, resource or other logistical constraints. The Cochrane Rapid Reviews Methods Group recommends further methodological development and publishing protocols to improve the transparency and quality of the review. The authors of this paper were invited to provide timely, expert input for the revision of the 2010 Guidelines for Providing Palliative and End of Life Care for People with Diabetes (Guidelines), Australia, regarding the evidence-based use of traditional and complementary medicine (T&CM). The inclusion and consideration of T&CM in guidelines is often ad-hoc and would benefit from more systematic methods. Evidence of efficacy on clinical outcomes is not the only reason to review an intervention. Other reasons relevant to the T&CM context is: interventions that are commonly used by people with diabetes in the palliative care setting, have potentially high costs or risks, or present a conflict in choices between individual and societ...

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“…Public interest in and demand for complementary medicine services have increased in recent years in Israel (Kitai et al 1998;Shmueli and Shuval, 2004) and throughout the Western world (Eisenberg et al 1993;Zollman and Vickers, 1999;MacLennan et al 1996;Garaghan, 1994;Shekelle et al 2005). Complementary medicine includes several therapeutic methods, all aimed at improving the patient's health and quality of life (Leibovici, 1996).…”

Section: Introductionmentioning

confidence: 99%

The Effect of Acupuncture on Blood Pressure in Hypertensive Patients Treated in a Complementary Medicine Clinic

Weil

Friger

Press

et al. 2007

Integr Med�Insights

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Background: Hypertension is a major health problem with serious medical and fi nancial consequences. Experimental studies in animals and clinical studies in humans have demonstrated that acupuncture can reduce blood pressure signifi cantly in hypertensive patients. The objective was to assess the effect of acupuncture on blood pressure in hypertensive patients treated at a complementary medicine clinic.

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Challenges in Systematic Reviews of Complementary and Alternative Medicine Topics

Cited by 71 publications

References 33 publications

Hepatoprotective effect ofAmomum xanthoidesagainst dimethylnitrosamine-induced sub-chronic liver injury in a rat model

Hepatoprotective effect ofAmomum xanthoidesagainst dimethylnitrosamine-induced sub-chronic liver injury in a rat model

Protocol for a Rapid Evidence Review of Traditional and Complementary Medicine for People with Diabetes Receiving Palliative or End-of-Life Care

The Effect of Acupuncture on Blood Pressure in Hypertensive Patients Treated in a Complementary Medicine Clinic

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