Challenges in orthopaedic management of Parkes-Weber syndrome

Ferreira, Mara Silva; Francisco, Telma; Tavares, Delfin

doi:10.1136/bcr-2013-008800

Cited by 2 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Right leg Primary angiosarcoma of the affected leg with systematic metastases Ismail et al 24 16 39 16/M Asymptomatic Right leg Positive family history for PWS; no genetic evaluation Schaal et al 40 29/F Limb enlargement during pregnancy…”

Section: Search Resultsmentioning

confidence: 99%

“…In case of embolotherapy, coil, nBCA (n-Butyl cyanoacrylate), and alcohol particles were used as embolic agents. According to Ferreira et al 39 16/M no n.a. Schaal et al 40 29/F A spontaneous delivery; compression therapy LMWH…”

Section: Pws and Venous Ulcerations/distal Arterial Ischemiamentioning

confidence: 99%

“…23,33 Positive family history and genetic evaluation Six (12.5%) cases were reported to have a positive family history for CVMs (three cases had relatives with CM, 26,48 and three cases had relatives with PWS). 25,38,39 The genetic evaluation was performed only in three cases, where two were RASA1 positive (mother had CM in both cases) and one was RASA1 negative (father had PWS). 38,48…”

Section: Pws and Malignancymentioning

confidence: 99%

See 2 more Smart Citations

Parkes Weber syndrome—Diagnostic and management paradigms: A systematic review

et al. 2016

View full text Add to dashboard Cite

Objectives Parkes Weber syndrome is a congenital vascular malformation which consists of capillary malformation, venous malformation, lymphatic malformation, and arteriovenous malformation. Although Parkes Weber syndrome is a clinically distinctive entity with serious complications, it is still frequently misdiagnosed as Klippel-Trenaunay syndrome that consists of the triad capillary malformation, venous malformation, and lymphatic malformation. Methods We performed a systematic review investigating clinical, diagnostic, and treatment modalities of Parkes Weber syndrome (PubMed/MEDLINE, Embase, and Cochrane databases). Thirty-six publications (48 patients) fulfilled the eligibility criteria. Results The median age of patients was 23 years (IQR, 8-32), and 24 (50.0%) were males. Lower extremity was affected in 42 (87.5%) and upper extremity in 6 (12.5%) patients; 15 (31.3%) patients developed high-output heart failure; 12 (25.0%) patients had chronic venous ulcerations, whereas 4 (8.3%) manifested distal arterial ischemia. The spinal arteriovenous malformations were reported in six (12.5%) patients and coexistence of aneurysmatic disease in five (10.4%) patients. The most frequently utilized invasive treatments were embotherapy followed by amputation and surgical arteriovenous malformation resection, and occasionally stent-graft implantation. All modalities showed clinical improvement. However, long follow-up and outcome remained unclear. Conclusion A diagnosis of Parkes Weber syndrome should be made on the presence of capillary malformation, venous malformation, lymphatic malformation, and arteriovenous malformation (as main defect) in overgrowth extremity. Arteriovenous malformation presents the criterion for distinguishing Parkes Weber syndrome from Klippel-Trenaunay syndrome, which is substantial for treatment strategy. The primary management goal should be patient's quality of life improvement and complication reduction. Embolization alone/combined with surgical resection targeting occlusion or removal of arteriovenous malformation "nidus" reliably leads to clinical improvement.

show abstract

Section: Search Resultsmentioning

confidence: 99%

Section: Pws and Venous Ulcerations/distal Arterial Ischemiamentioning

confidence: 99%

Section: Pws and Malignancymentioning

confidence: 99%

See 1 more Smart Citation

Parkes Weber syndrome—Diagnostic and management paradigms: A systematic review

et al. 2016

View full text Add to dashboard Cite

show abstract

“…M.S. Ferreira [49] рекомендує подовження сегментів здорової нижньої кінцівки для корекції гіпертрофії кінцівки на фоні АВМ.…”

Section: вступunclassified

Vascular Malformation as an Orthopedic Problem (Review)

Zyma

Kincha-Polishchuk

Cheverda

et al. 2020

HOTP

View full text Add to dashboard Cite

Summary. Scientific research is analyzed and highlights the modern views on the problem of orthopedic manifestations of vascular malformations. The achievements of scientists concerning etiology, pathogenesis, classification, orthopedic manifestations and treatment of pathology of the musculoskeletal system at vascular malformations are described. The authors also identified key unexplained practical issues of orthopedic manifestations in this nosology and announced ways to solve them.

show abstract

Challenges in orthopaedic management of Parkes-Weber syndrome

Cited by 2 publications

References 8 publications

Parkes Weber syndrome—Diagnostic and management paradigms: A systematic review

Parkes Weber syndrome—Diagnostic and management paradigms: A systematic review

Vascular Malformation as an Orthopedic Problem (Review)

Contact Info

Product

Resources

About