“…• SEC-RI (pullulan calibration) (Hasegawa et al, 1994;Knill et al, 2005;Lin & Lin, 2003) • SEC-LALS (Kubota et al, 2000;Ottøy et al, 1996Ottøy et al, , 1995 • SEC-MALS (Tømmeraas et al, 2002;Sorlier et al, 2001;Sorlier, 2002;Berth et al, 1998;Lamarque et al, 2004Lamarque et al, , 2005Schatz et al, 2003;Brugnerotto et al, 2001) • SEC-LALS-Vis (Weinhold et al, 2009) • SEC-MALS-Vis (Christensen et al, 2008) Since the use of size-exclusion chromatography is commonly agreed upon, more controversy is present about surrounds the different detectors used online for chromatography. Nowadays, all the old bench methods can be applied to a chromatography setup such as a refractive index detector (RI), viscosity detector (Vis) and light-scattering detectors (single-90°, low-angle and 90° (LALS), or multi-angle with 3, 5, or up to 18 angles (MALS).…”