Çeşitli Klinik Örneklerden İzole Edilen Staphylococcus aureus Suşlarının Antibiyotik Direnç Oranları

Abstract

Objective: Staphylococcus aureus is an important pathogen that can cause both community and hospital-acquired infections. The presence of methicillin resistant isolates limits treatment options. The aim of this study was to determine the antibiotic resistance rates in S. aureus strains isolated from outpatients and inpatients in our hospital. Method: Various clinical specimens were evaluated retrospectively between 2016-2019 and S. aureus strains were included in the study. Bacterial identification and antibiotic susceptibility tests were performed using conventional methods and automated systems. Results: In our study, 595 S. aureus strains were assessed. The strains included in the study were most frequently isolated from blood and wound samples. One hundred and seventy-two isolates (28.9%) were identified as methicillin resistant S. aureus (MRSA). The resistance rates to erythromycin, tetracycline, clindamycin, gentamicin, ciprofloxacin and trimethoprim-sulfamethoxazole were 16.8% or below. High resistance rates were observed in MRSA against these antimicrobials compared to methicillin-susceptible S. aureus (MSSA) strains. Resistance was not found against vancomycin, teicoplanin and linezolid, whereas resistance to daptomycin was 0.7%. Conclusion: Antibiotic resistance is one of the most important health problems of today.Resistance to both methicillin and other antibiotics decreases the success rates of treatment in S. aureus infections. Therefore, it is very important to regularly monitor antibiotic resistance surveillance.

Antibiotic and Heavy Metal Resistance Patterns of Indicator Bacteria in Surface Water Bodies of Kilis

“…In this present investigation, 50.0% Gr negative bacteria isolated from St1 were resistant to ceftazidime, cefotaxime, clindamycin, and ampicillin, whereas only %25 of the isolates from St2 showed clindamycin and cefotaxime resistance. Although the prevalence of ARB in many freshwater sources of Turkey has been previously reported (Ozgumus et al 2009;Akkan et al 2011), this is the first study that indicated the high frequency of ampicillin and clindamycin resistance in surface waters of Kilis. Buyukkaya Kayıs (2022) noted that E. coli isolated from 5 different stations in Ataturk Dam in Adıyaman was resistant to chloramphenicol, and tetracycline antibiotics contrary to our findings.…”

N-Aseti̇l Si̇stei̇ni̇n Acinetobacter Baumannii İzolatlarina Karşi Anti̇mi̇krobi̇yal Etki̇si̇ Ve Anti̇bi̇yoti̇klerle Etki̇leşi̇mi̇

“…A. baumannii can be found in nature and in human skin flora or may be isolated from clinical specimens [7][8]. Resistance to antibiotics used in infections caused by these strains has become a significant global health problem, as increasing multi-antibiotic resistance reduces the possibility of treatment [9,10]. Many Acinetobacter species have shown resistance to antibiotics such as quinolones, carbapenems, and cephalosporins.…”

İdrar Kültürleri̇nden İzole Edi̇len Escheri̇chi̇a Coli̇ Suşlarinin Kli̇ni̇kte Sikça Kullanilan Anti̇bi̇yoti̇klere Karşi Di̇renç Oranlarinin Araştirilmasi

“…Mevcut direnç oranlarıyla TMP-SMX bölgemizde sistit tedavisinde ampirik tedavi için uygun bir ajan haline gelmiştir. Ülkemizde E. coli'ye karşı florokinolon direnci %7-41 arasında değişmektedir (11,(14)(15)(16)(17)(18). Bizim çalışmamızda bu oran %20.73 olup Türkiye geneliyle benzerdir.…”