“…In the past, NTM generally have shown poor in vitro susceptibility to standard antituberculous drugs, 14 and many authors have recommended surgical interventions including partial or total parotidectomies for NTM infection of the parotid gland lymph nodes. 13,15,16 Conversely, many studies show that clarithromycin, amikacin, cefoxitin, fluoroquinolones (ciprofloxacin and ofloxacin), doxycycline, imipenem, and sulfonamides have good in vitro activity against M. fortuitum. 17,18 A combina- tion of 2 or more agents should always be utilized, as with all mycobacterial infections, to avoid drug resistance.…”