Cervical twin ectopic pregnancy after In Vitro fertilization-Embryo transfer (IVF-ET): case report

Abstract

Transvaginal ultrasound-guided aspiration and systemic methotrexate administration can be safely and easily used to treat cervical ectopic pregnancies and to preserve the fertility of the patient without any major complications.

Cervical ectopic pregnancy after in vitro fertilization: case report successfully treated with cervical electric aspiration

“…The literature reports 12 cases of exclusive cervical ectopic pregnancy after IVF-ET (Weyerman et al ., 1989; Bennett et al ., 1993; Ginsburg et al, 1994; Saliken et al, 1994; Pattinson et al, 1994. Two cases of twin cervical ectopic pregnancy, rarer, are reported by Anev et al (2013) and by Aboulfoutouh et al (2011). In all other cases, cervical ectopic pregnancy after IVF-ET was heterotopic.…”

“…Hysteroscopic resection was alternative to Jozwiak et al (2003) to treat cervical heterotopic pregnancy and maintain intrauterine pregnancy to term successfully. The use of methotrexate for the treatment of cervical heterotopic gestation is described by authors such as Bratta et al (1996), Hsieh et al (2004), Aboulfoutouh et al. (2011), Sánchez-Ferrer et al (2011) and Tsakos et al (2015).…”

“…In an unusual case, Anev et al (2013) describe a diamniotic and monochorionic twin cervical ectopic pregnancy after single ET, diagnosed at week 6 and treated with the combination of mifepristone and systemic methotrexate, followed by aspiration cervical emptying. Aboulfoutouh et al (2011) also reported a case of twin cervical ectopic pregnancy after IVF-ET, but opted for ultrasound-guided aspiration and single methotrexate systemic injection. Sieck et al (1997) have been successful in employing exclusive methotrexate to treat cervical ectopic pregnancy.…”

Ectopic Pregnancy and Assisted Reproductive Technologies: A Systematic Review

“…Twin pregnancy in the uterine cavity continue to grow till article publication (at 12 th week of pregnancy). A cervical twin ectopic pregnancy has been described by Aboulfoutouh et al (Aboulfoutouh et al, 2011). Treatment consistent from transvaginal ultrasound-guided aspiration plus systemic single injection of methotrexate.…”

Selective reduction of a triplet heterotopic cervical pregnancy after embryo transfer

“…Different treatments for ectopic cervical pregnancy are described in the literature: systemic Methotrexate injection [20][21][22], uterine artery embolization or ligation [23] [24], transvaginal ultrasound-guided aspiration [23], KCl solution [25], Methotrexate [13,26,27] or hyperosmolar glucose injection into the gestational sac [28], cervical curettage with balloon tamponnade [29][30][31] or Shirodkar cerclage to make hemostasis [32]. Olav describes a hysteroscopy resection of a cervical pregnancy because of bleeding after Methotrexate treatment [33].…”