Cervical conization for diagnosis and treatment of carcinoma in situ

Early Cervical Neoplasia Confirmed by Conization

“…Conization of the cervix is recommended as the diagnostic procedure in patients with an abnormal cytologic smear because of its accuracy. 4,8,13,17,18,25 In our department, conization is performed on women with severe dysplasia, CIS or mi- croinvasive carcinoma and for excluding occult frankly invasive carcinoma. Treatment failures with cryosurgery and laser vaporization have been described.…”

“…Conization is considered the best diagnostic and therapeutic procedure because sufficient tissue and consecutive sections are obtained. 1,4,8,13,17,18,25 The purpose of this study was to elucidate the accuracy of cytology, colposcopy and punch biopsy as compared with the final pathologic diagnosis on cone or punch biopsy specimens in early cervical neoplasia.…”

Conization for Preinvasive and Early Invasive Carcinoma of the Uterine Cervix

“…The first to propose that a cone with margins free from atypic cells was treatment enough for CIS irrespective of age and desire for further childbirth were Enterline and Krieger & McCormack (118,219,220, Their proposal prompted several investigators to study the frequency of persistent disease in hysterectomy specimens after conization (23,48,103,126,144,146,159,161,181,258,264,278,307,309,334,341,344,350,370,393,405). Reported figures vary between 10 and 70%.…”