Certain hormonal profiles of postpartum anestrus jersey crossbred cows treated with controlled internal drug release and ovsynch protocol

Abstract

Aim:The study was conducted to determine the serum levels of certain hormones in post-partum anestrus cows following treatment with controlled internal drug release (CIDR) and Ovsynch protocol.Materials and Methods:A total of 30 postpartum anestrus cows were divided into three equal groups after thorough gynecoclinical examination. The Group 1 animals received an intravaginal progesterone device on day 0 and 2 ml of prostaglandin F2α (PGF2α) on day of CIDR removal (7th day), Group 2 cows were treated with ovsynch protocol (gonadotropin-releasing hormone [GnRH]-PGF2α-GnRH) on day 0, 7 and 9, respectively, and Group 3 cows were supplemented with mineral mixture and treated as control. The serum estrogen, progesterone, triiodothyronine, and thyroxine concentration were estimated using enzyme-linked immunosorbent assay kit and absorbance was read at 450 nm with Perkin Elmer Wallac 1420 Microplate Reader.Results:There was a significant increase in progesterone level in Group 1 after withdrawal of CIDR as compared to other two groups. However, the estrogen assay revealed a greater concentration in Group 2 against Group 1 on day 7 of sampling. However, there was no significant difference for serum triiodothyronine (T3) and thyroxine (T4) irrespective of treatment protocols and days of sampling.Conclusion:Treatment with CIDR based progesterone therapy and drug combinations may affect the reproductive hormonal balance like estrogen and progesterone, which is inevitable for successful return to cyclicity and subsequent fertilization and conception. However, as far as serum T3 and T4 concentration concerned it may not give an astounding result.

Effect of progesterone coated nano fibre dermal patch (ProSync-NF) on cattle diagnosed with Anestrus and silent or unobserved estrus

“…On the Day 5, i.e. on the day of dermal patch removal in Group I, Progesterone level increased as compared with the Day 0, which is comparable as described by Syafnir et al 2011 andJena et al 2016. Hence it could be inferred that ProSync-NF dermal patch has the effect on increasing progesterone level after affixing it on the depilated skin of the animals under treatment.…”

“…In all the reproductive problems in dairy cattle, Anestrus is the most important clinical manifestation that ends up in the substantial losses to the farmers due to reduced calf crop with high treatment cost (Parkinson T J 2019). Anestrus in cattle is generally described as failure of estrus due to functional disturbances in the ovary, many at times characterized by ovary without any of the palpable structures (Ambrose D J 2015, Jena et al 2016, Parkinson T J 2019. In another scenario animal may be regularly cycling but the owner fails to identify the estrus.…”

1H NMR plasma metabolomic profiling of ovarian quiescence in energy balanced postpartum dairy cows

“…In recent years, with the increase of average milk yield in the global dairy industry, anestrus in high-producing dairy cows is becoming increasingly problematic (Jena et al. 2016), causing low reproduction rates, extended periods of infertility and calving intervals, with serious consequences to dairy farm economics. Ovarian quiescence has been accepted as the most common cause of anestrus in high-producing cows.…”

Effect of progesterone on some fertility performances in cattle

“…Similar findings were reported in Egypt by Saad and EL-Nabawy (2013) who stated that there was a significant increase in serum progesterone at the end of treatment in CIDR-PG treated group, and in the same way Mehni et al (2012) who studied the effect of CIDR on sixty-four lactating Holestian dairy cows reported that there was a significant increase in serum progesterone after end of treatment. Furthermore Jena et al (2016) recorded that there was a significant increase in serum progesterone level of jersey crossbred cows treated with CIDR.…”