“…It has been subsequently found that somatostatin is widely distributed in the central nervous system (CNS), the pancreas, and the gastrointestinal tract, where it acts as a neurotransmitter/ neuromodulator and a hormone (for review, see Epelbaum et al, 1994;Viollet et al, 2000). The distribution of somatostatin in the CNS has been described in various vertebrate taxa, including mammals (for review, see Johannson et al, 1984), birds (Hoffman and Hayes, 1979;Takatsuki et al, 1981;Blä hser, 1984;Trabucchi et al, 2003), reptiles (Doerr-Schott and Dubois, 1977;Fasolo and Gaudino, 1982;Bear and Ebner, 1983;Weindl et al, 1984;Reiner and Oliver, 1987), amphibians (Rémy and Dubois, 1978;Vandesande and Dierickx, 1980;Inagaki et al, 1981;Blä hser et al, 1982;Yui, 1983;Olivereau et al, 1984c;Adli et al, 1988;Laquerrière et al, 1989;Vallarino et al, 1998;Petko and Orosz, 1996;Stuesse et al, 2001), and several groups of fishes, i.e., lungfish (Vallarino et al, 1997;Trabucchi et al, 1999), teleosts (Olivereau et al, 1984a,b;Verdonck and Ollevier, 1984;Lin et al, 1999), chondrosteans (Trabucchi et al, 2002), elasmobranch (Nozaki, 1985), and in cyclostomes (Nozaki and Gorbman, 1983;Wright, 1986;Cheung et al, 1991;Yañ ez et al, 1992). Somatostatin-like immunoreactivity h...…”