Cerebral venous thrombosis in a patient with ulcerative colitis

Chauhan, Sandeep; Sachdev, Atul; D’Cruz, Sanjay; Jain, Koyal; Singh, R. B.

doi:10.1002/ibd.20236

Cited by 9 publications

(6 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Forty-nine cases of MRI-diagnosed CVT in IBD were found in the literature (1989–2010) (9–45) including 31 single case reports. The largest series included six adult patients (42).…”

Section: Resultsmentioning

confidence: 99%

Cerebral Venous Thrombosis in Inflammatory Bowel Diseases: Eight Cases and Literature Review

Cognat

Crassard

Denier

et al. 2011

International Journal of Stroke

View full text Add to dashboard Cite

In our cerebral venous thrombosis cohort, inflammatory bowel disease is present in 2 · 3% of cases. As cerebral venous thrombosis has no specific feature and may reveal inflammatory bowel disease, intestinal signs should be systematically looked for. All physicians caring for inflammatory bowel disease patients must consider cerebral venous thrombosis in cases of unusual headache or focal neurological symptoms. Treatment is based on full anticoagulation and specific inflammatory bowel disease treatment.

show abstract

“…Forty-nine cases of MRI-diagnosed CVT in IBD were found in the literature (1989–2010) (9–45) including 31 single case reports. The largest series included six adult patients (42).…”

Section: Resultsmentioning

confidence: 99%

Cerebral Venous Thrombosis in Inflammatory Bowel Diseases: Eight Cases and Literature Review

Cognat

Crassard

Denier

et al. 2011

International Journal of Stroke

View full text Add to dashboard Cite

show abstract

“… 4 Additionally, anemia and thrombocytosis have been suggested as significant risk factors for CVT. 4 9 Coagulation abnormalities (increased fibrinogen, elevated factor VII, elevated factor VIII, antithrombin III deficiency, and protein C and protein S deficiency) often coexist with IBD and return to normal values when the intestinal inflammation is controlled. Antiphospholipid antibodies (aPLs) were also present in some IBD patients with CVT.…”

Section: Discussionmentioning

confidence: 99%

A case of ulcerative colitis presenting with cerebral venous thrombosis

et al. 2018

View full text Add to dashboard Cite

Patients with inflammatory bowel disease (IBD) have been reported to have an increased risk of thromboembolism. Cerebral venous thrombosis (CVT) is a rare but serious extraintestinal manifestation of IBD. Due to its highly variable manifestation and low incidence, CVT is not usually readily recognized by physicians. Herein, we report a case of a 35-year-old male presenting with CVT associated with ulcerative colitis (UC). The patient was admitted with chief complaints of bloody diarrhea that had started 3 days prior. Sigmoidoscopy showed hyperemic and edematous mucosa, friability, and shallow ulcers from the sigmoid colon to the rectum suggestive of IBD. Three days later, the patient started complaining of a headache, and gradually developed a decreased level of consciousness. Magnetic resonance imaging of the brain revealed CVT with hemorrhagic infarctions. An angiogram was obtained to evaluate the extent of CVT, and anticoagulation therapy was initiated with intravenous heparin. During hospitalization, he was diagnosed with UC and treated with 5-aminosalicylic acid. After discharge, the patient was recovered without neurological deficit, and remission of UC was also obtained. The presence of headache or acute worsening of neurological status in a patient with IBD should alert the health professionals about the possibility of CVT.

show abstract

“…It has been postulated that mucosal inflammation is responsible for the increased coagulant activity, but even patients with UC have been reported to have CVT after colectomy, as was the case in one of our patients (patient no. 1) …”

Section: Discussionmentioning

confidence: 99%

Cerebral venous thrombosis in inflammatory bowel disease

DeFilippis

Barfield

Leifer

et al. 2015

J of Digest Diseases

View full text Add to dashboard Cite

Cerebral venous thrombosis (CVT) is a rare but devastating complication of inflammatory bowel disease (IBD). Here we describe six IBD patients with cerebral venous thrombosis. The patients presented with hours to days of headache and were found to have venous thrombosis on imaging. Four of the six patients had ulcerative colitis and two had Crohn's disease. All six patients were treated with therapeutic anticoagulation. There were two deaths; one patient became comatose and died despite anticoagulation while the other recovered well from the sinus thrombosis but died after a bowel perforation 3 weeks later. This case series demonstrates the critical need for early recognition of neurological symptoms in patients with IBD during disease flares. It is important to recognize the clinical signs in order to start anticoagulation expeditiously and improve neurological outcomes.

show abstract

Cerebral venous thrombosis in a patient with ulcerative colitis

Cited by 9 publications

References 8 publications

Cerebral Venous Thrombosis in Inflammatory Bowel Diseases: Eight Cases and Literature Review

Cerebral Venous Thrombosis in Inflammatory Bowel Diseases: Eight Cases and Literature Review

A case of ulcerative colitis presenting with cerebral venous thrombosis

Cerebral venous thrombosis in inflammatory bowel disease

Contact Info

Product

Resources

About