Cerebellar Toxoplasmosis in HIV/AIDS: A Case Report

Abstract

RÉSUMÉ CONTEXTE: Toxoplasma encéphalite est une présentation commune des T gondii infection oxoplasma du système nerveux central dans la phase tardive de l'immunodéficience humaine virale (VIH). Le diagnostic définitif nécessite la démonstration de la toxoplasmose dans le tissu cérébral. Toutefois, la démonstration neuro-radiologie (en utilisant la tomodensitométrie ou imagerie par résonance magnétique) de l'anneau d'aide à l'unique ou multiple focal lésions intracrâniennes, en présence de l'immunosuppression et une réponse rapide au traitement présomptif sont de diagnostic en l'absence d'installations histologique. La rareté des lésions toxoplasmiques dans le cervelet provoque un indice élevé de suspicion clinique et l'établissement précoce d'un traitement présomptif en Afrique sub-saharienne des ressources des pays

Toxoplasmosis in HIV/AIDS Patients - A Living Legacy

“…A case of CT with massive intracerebral hemorrhage leading to a fatal vehicular crash was also reported in a patient with AIDS (Gyori & Hyma, 1998). Cerebellar toxoplasmosis is another infrequent complication of HIV/AIDS that should prompt a high index of clinical suspicion and early institution for presumptive therapy in poor resource settings (Emeka et al, 2010). These unusual neurological presentations of AIDS patients associated toxoplasmosis have rarely been reported in Asia (Chaddha et al, 1999;Nissapatorn et al, 2004;Subsai et al, 2006;Nissapatorn et al, 2007).…”

Toxoplasmosis in Nigeria: the story so far (1950-2016): a review

“…In individuals with AIDS, this disease could lead to death Remington 1992, Luft et al 1993). However, symptoms such as encephalitis, seizures hemiparesis, subacute focal deficits anxiety, loss of consciousness, headache and other mental disturbances could ensue following cyst rupture in the brain (Weiss and Kim 2007, Emeka et al 2010, Philib-Ephraim et al 2015.…”

A Report of Two Cases with Different Clinical Presentation of Cerebral Toxoplasmosis in HIV-Infected Bulgarian Patients

“…A third of the cases have solitary, several (two to five), or multiple (more than five) lesions. In 90% of the cases, ring enhancement is found around the lesions, often accompanied by edema [1][2][3][4]. Up to 97% of patients with cerebral toxoplasmosis have IgG antibodies.…”

“…A febrile psychosyndrome with confusion is also a frequent early sign. It is not unusual to see an epileptic seizure as the initial presentation, in the absence of other symptoms [1][2][3][4][5][6]. Cerebral toxoplasmosis seldom occurs above a CD4 count of 100 cells/µl; over 200 CD4 cells/µl it is very rare.…”

“…Cerebral toxoplasmosis seldom occurs above a CD4 count of 100 cells/µl; over 200 CD4 cells/µl it is very rare. To determine the diagnosis, a CT or MRI scan of the head should be performed promptly in each case of a focal neurological deficit [3,4,6]. MRI is superior to a CT scan, and almost always shows more visible lesions [4].…”