Cerebellar Purkinje cell-specific protein-like immunoreactivity in noradrenalin-chromaffin cells and ganglion cells but not in adrenaline-chromaffin cells in the rat adrenal medulla.

Kondo, Hisatake; Kuramoto, Hirofumi; Iwanaga, Toshihiko; Fujita, Tsuneo

doi:10.1679/aohc.48.421

Cited by 17 publications

(3 citation statements)

References 11 publications

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“…As fixation with 4% paraformaldehyde is suitable for demonstrating noradrenaline fluorescence, some sections were examined using a fluorescence microscope for catecholamine visualization (Falck and Torp 1961;Eränkö 1967;Kondo et al 1985). After photography, the sections were immunostained as described above.…”

Section: Light Microscopymentioning

confidence: 99%

“…Calbindin D-28k was known to lack immunoreactivity in the intra-adrenal nerve fibers of rats (Kondo et al 1985); however, a recent study by Ren and Ruda (1994) revealed that calbindin D-28k existed in many neurons of the spinal intermediolateral nucleus of rats. Since numerous nerves supplying the adrenal medulla are mostly preganglionic sympathetic nerves originating from the intermediolateral nucleus in the rat spinal cord (Kesse et al 1988), the discrepancy of calbindin D-28k-distribution in the spinal neuron is not known.…”

Section: Introductionmentioning

confidence: 96%

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Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla

Iino

Kobayashi

Hidaka

1997

Cell and Tissue Research

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Neurocalcin is a novel calcium-binding protein found in bovine brain tissue. We investigated immunoreactivity for neurocalcin in the mouse adrenal medulla using light and electron microscopy. The immunoreactivity was present in nerve fibers, nerve terminals, and ganglion cells in the adrenal medulla, but chromaffin cells, sustentacular cells, and Schwann cells were negative in reaction. Nerve bundles containing neurocalcin-immunoreactive fibers passed through the adrenal cortex and extended into the medulla. Immunopositive nerve fibers branched off and projected varicose terminals around the chromaffin cells. These varicose terminals contained small and large-cored vesicles and made synapses with the chromaffin cells. We performed paraformaldehyde-induced fluorescence-histochemical studies for catecholamine combined with immunohistochemical studies for neurocalcin. Neurocalcin-immunoreactive nerve terminals were more abundant at noradrenaline (fluorescent) cell-rich regions than at adrenaline (non-fluorescent) cell-rich regions. These results show that neurocalcin-immunoreactive nerves mainly innervate noradrenaline-containing chromaffin cells in the mouse adrenal medulla and that neurocalcin may regulate synaptic function in the nerve terminals.

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Section: Light Microscopymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 96%

Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla

Iino

Kobayashi

Hidaka

1997

Cell and Tissue Research

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“…The immunohistochemical studies using an antiserum against spot 35 protein have shown its specific localization in the Purkinje cell throughout the course of the late prenatal and the postnatal development of the cerebella of rats (Yamakuni et al, 1984;TakahashiIwanaga et al, 1986). Further immunohistochemical studies have revealed the occurrence of spot 35-like immunoreactivity in several receptor cells and endocrine cells outside the central nervous system Kondo et al, 1985). In the retina of adult rats the horizontal cells exhibit intense immunoreactivity for spot 35 protein, but amacrine cells in the inner zone of the inner nuclear layer and in the ganglion cell layer exhibit faint to moderate immunoreactivity for it.…”

mentioning

confidence: 99%

An immunohistochemical study of the ontogeny of the horizontal cell in the rat retina using an antiserum against spot 35 protein, a Novel purkinje cell‐specific protein, as a marker

et al. 1988

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A sequence of morphological changes during the differentiation of retinal horizontal cells was studied by means of immunohistochemistry for spot 35 protein, a novel Purkinje cell-specific protein, in the rat retina. Spot 35-immunoreactive horizontal cell anlagen were first identified at embryonic day 18 (E18) in the outer zone of the neuroblastic cell layer as fusiform cells with slender inner and outer processes. As the development proceeded, the immunoreactive cells increased in number and intensity of the immunostaining, and the outer processes of the immunoreactive cells were often bifurcated close to their origin or at their periphery. At postnatal days 3 and 5 (P3 and P51, a regional difference in morphology of the immunoreactive horizontal cell anlagen was recognized: The immunoreactive cells near the ora serrata still assumed a bipolar shape, and those in the central portion of the retina had multiple processes. At P7 and P10, the immunoreactive cells in the periphery of the retina extended most of their outer processes in the plane of the retina, forming a network together with processes of adjacent immunoreactive horizontal cells. Their internally extending processes during these postnatal stages tended to be present in small numbers and to be short. At P14 all the immunoreactive horizontal cells extended their processes horizontally to form a tight bundle all the way along the outer plexiform layer. These findings indicate that spot 35 protein is a specific marker for the horizontal cells of the rat retina in the developmental process from their bipolar stage at El8 until reaching their mature configuration at P14.

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Immunohistochemical and In Situ Hybridization. Evidence for a Calcium-Binding Protein in the Sinus Nerve

Kondo¹,

Yamamoto²,

Goto³

1990

Arterial Chemoreception

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Cerebellar Purkinje cell-specific protein-like immunoreactivity in noradrenalin-chromaffin cells and ganglion cells but not in adrenaline-chromaffin cells in the rat adrenal medulla.

Cited by 17 publications

References 11 publications

Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla

Heterogeneous distribution of neurocalcin-immunoreactive nerve terminals in the mouse adrenal medulla

An immunohistochemical study of the ontogeny of the horizontal cell in the rat retina using an antiserum against spot 35 protein, a Novel purkinje cell‐specific protein, as a marker

Immunohistochemical and In Situ Hybridization. Evidence for a Calcium-Binding Protein in the Sinus Nerve

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