Ceramic Nanofiber Materials for Wound Healing and Bone Regeneration: A Brief Review

Gomes, Déborah dos Santos; Victor, Rayssa de Sousa; Sousa, Bianca Viana de; Neves, G. A.; Santana, Lisiane Navarro de Lima; Menezes, Romualdo Rodrigues

doi:10.3390/ma15113909

Cited by 12 publications

(2 citation statements)

References 190 publications

(267 reference statements)

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“…Bone regeneration is also an urgent problem to be solved in tissue engineering, and also faces the problem that hypoxia affects bone regeneration and repair. [ 194 ] Currently, most tissue‐engineered scaffolds lack a functional vascular network, leading to scaffold hypoxia, hindering the repair and regeneration of bone tissue. [ 195 ] The provision of additional oxygen can greatly accelerate bone regeneration by overcoming hypoxia and providing sufficient oxygen for cell survival and differentiation before blood vessel formation.…”

Section: Microbial‐enabled Photosynthetic Oxygenation For Tissue Engi...mentioning

confidence: 99%

Microbial‐Enabled Photosynthetic Oxygenation for Disease Treatment

Yang,

Li,

Feng

et al. 2023

Adv Funct Materials

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Oxygen as one of the most critical substances in living organisms has attracted ever‐increasing attention in disease treatment, which is important in regulating metabolic activities. However, the hypoxia arising from disease is a prevalent problem, leading to observably reduced therapeutic effectiveness in photodynamic therapy, radiotherapy, sonodynamic therapy, etc. Therefore, the reversion of hypoxia becomes the basis for enhancing the disease treatment. Thanks to the development of nanotechnology, various nanomaterials with oxygen‐production capacity are explored to recover the function of oxygen in tissue, but there are still some limitations. The photosynthetic microorganisms (PSMs) are extensively applied for improving hypoxia in diseases due to their highly efficient photocatalytic oxygen production efficacy and desirable biocompatibility. In this review, the up‐to‐date research progress on therapeutic modalities of microbial‐based photosynthetic oxygenation (e.g., cancer treatment, wound healing, and tissue engineering) are summarized and highlighted. In addition, the key issue of biocompatibility/biosafety of microbial‐based treatment that is fundamental to apply in vivo is further emphasized and clarified. Finally, the present critical issues are discussed and the future evolution of microbial‐based treatment based on photosynthetic oxygenation is predicted, promoting further development and clinical applications.

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Section: Microbial‐enabled Photosynthetic Oxygenation For Tissue Engi...mentioning

confidence: 99%

Microbial‐Enabled Photosynthetic Oxygenation for Disease Treatment

Yang,

Li,

Feng

et al. 2023

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

“…8 Ceramic nanofibers are generally used with the integration of synthetic or natural polymers in wound repair approaches because of their bioactivity and biodegradability characteristics. 9 Polymers with low toxicity are often used in tissue engineering and drug delivery applications through further modifications. 10 Additionally, the biocompatible self-assembled NPs have vast potential to closely mimic the natural ECM that can be functionally developed to increase their communication with other cells.…”

Section: Introductionmentioning

confidence: 99%