“…29 Infections in general (sepsis, local infections, and infections at insertion site) occurred in 0% to 21% of patients with PICCs [4][5][6]11,[13][14][15]18,23,26,27,33,35,37,44,[47][48][49] versus 0% to 14% with PIVCs 6,10,14 and 0% to 35% with CVCs. 5,6,11,33 In the study by Toure et al, 33 catheter-associated infection (exit site, tunnel, or pocket infection) rate was lower in patients receiving HPN by PICCs versus CICCs (1.05 vs. 1.87 per 1000 catheter days, P = 0.01). Rates of central line-associated bloodstream infections (CLABSI) with PICCs were 0% to 5.7%, 12,15,26,47 and CLABSI was not assessed in the studies of PICCs and CICCs.…”