Highlights
Fifty-six studies were included in a systematic literature review. PICCs were compared to CICCs and PIVCs for short/intermediate-term use in Europe. Several efficacy and safety benefits were shown with PICCs. Limited evidence showed higher costs with PICCs.
A807patients (n= 102), analyses were performed on itch (assessed by a 0-10 numeric rating scale [NRS] ), Psoriasis Skin Appearance Bothersomeness (PSAB, score range 0-30), and HRQoL (assessed by the Dermatology Life Quality Index (DLQI; score range 0−30). Treatment comparisons were made using an ANCOVA model with missing values imputed by last observation carried forward. Results: Patients treated with IXE had statistically significantly greater reductions in itch vs. ETN and PBO as early as week 1 (Q2W -3.
Objectives: To identify the economic impact of using the Validated Intraoperative Bleeding Scale (VIBe-SCALE) in Cardiovascular, Vascular and Thoracic surgeries in US hospitals. Methods: A Retrospective review of data from 72 Cardiovascular, Vascular and Thoracic surgeries performed August-December 2018, at multiple US Hospitals was performed to determine the economic impact of transfusion costs with the utilization of VIBe-SCALE. A 1000 iterations following a uniform distribution for blood product usage and normal distribution for blood product costs was performed to estimate a Budget Impact model that analyze the impact on the adoption of Active Hemostatics in Cardiovascular, Vascular and Thoracic procedures, in a 3-year scenario. Results: The average estimated blood loss (EBL) was 512 mL. Total blood products used included Packed Red Blood Cells 15U, Fresh Frozen Plasma and Platelets 10U, and Cryoprecipitate 52U. The average EBL for Cardiovascular was 10.52mL/min (VIBe-SCALE Grade 3), Vascular 7.98 mL/min and Thoracic 6.70 mL/min
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