2020
DOI: 10.5935/2595-0118.20200010
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Central sensitization and beliefs among patients with chronic pain in a primary health care unit

Abstract: BACKGROUND AND OBJECTIVES: The pain that persists for more than three months is classified as chronic pain. Current studies suggest the existence of a dynamic relationship between biological changes, psychological state, and social context within the pain phenomenon and its chronicity. Central sensitization can be defined as the amplification of the neural signaling within the central nervous system that causes pain hypersensitivity, characterized by overlapping symptoms. The objective of this study was to eva… Show more

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Cited by 3 publications
(3 citation statements)
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“…Most treatment strategies for CLBP are still based on the biomedical model, that is, structural-anatomicalmechanical [10]. However, the biopsychosocial model is based on a dynamic relationship between the biological changes, psychological status, and social context, emphasizing that these factors have different roles in chronic pain, disability, and emotional maladjustment [11]. Therefore, the present study aimed to investigate the association of the single nucleotide polymorphism (SNP) Val66Met of the BDNF gene with clinical and biopsychosocial factors in patients with CLBP.…”
Section: Introductionmentioning
confidence: 99%
“…Most treatment strategies for CLBP are still based on the biomedical model, that is, structural-anatomicalmechanical [10]. However, the biopsychosocial model is based on a dynamic relationship between the biological changes, psychological status, and social context, emphasizing that these factors have different roles in chronic pain, disability, and emotional maladjustment [11]. Therefore, the present study aimed to investigate the association of the single nucleotide polymorphism (SNP) Val66Met of the BDNF gene with clinical and biopsychosocial factors in patients with CLBP.…”
Section: Introductionmentioning
confidence: 99%
“…Due to the high prevalence of chronic pain in the general population, a paradigm shift in the approach to pain is essential. This involves a multi-professional and multimodal approach to pain management, focusing not only on pharmacological treatments but also on complementing them with non-pharmacological treatments [ 19 ].…”
Section: Introductionmentioning
confidence: 99%
“…There is strong evidence that chronic pain may be associated with physical disability, emotional disorders, and social difficulties. In addition, it has been recognized that emotional, cognitive, and social factors mediate the subjective experience of pain 6 .…”
Section: Introductionmentioning
confidence: 99%