Central retinal artery occlusion in Crohn disease

Falavarjani, Khalil Ghasemi; Parvaresh, Mohammad Mehdi; Shahraki, Kourosh; Nekoozadeh, Shahbaz; Amirfarhangi, Abdollah

doi:10.1016/j.jaapos.2012.03.004

Cited by 15 publications

(8 citation statements)

References 7 publications

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“…Falavarjani et al . reported a 9-year-old boy with CD who developed central retinal arterial occlusion [24]. In pathological examination of the brain tissue of a patient with IBD who suffered from a cerebrovascular event, Schneiderman et al .…”

Section: Discussionmentioning

confidence: 99%

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Nemati

Mehdizadeh

Salimipour

et al. 2017

Gastroenterology Report

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The neurological manifestations of Crohn’s disease and its prevalence are not well known. Here, we report five patients of confirmed Crohn’s disease with different neurological presentations. The neurological presentations include anterior ischemic optic neuropathy, myelopathy, posterior reversible encephalopathy syndrome, chronic inflammatory demyelinating polyneuropathy, and chronic axonal sensory and motor polyneuropathy. These manifestations should be kept in mind in the assessment of Crohn’s disease.

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Section: Discussionmentioning

confidence: 99%

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Nemati

Mehdizadeh

Salimipour

et al. 2017

Gastroenterology Report

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“…Crohn's disease has been reported to be associated with ischemic retinal vasculitis, NV [70], neovascular glaucoma [71], and CRAO [72]. West Nile virus infection has been associated with chorioretinitis as its most common ocular finding, whereas occlusive retinal vasculitis is an uncommon finding reported to date in eight cases.…”

Section: Other Causes Of Occlusive Retinal Vasculitismentioning

confidence: 99%

Ischemic Retinal Vasculitis and Its Management

Talat

Lightman

Tomkins-Netzer

2014

Journal of Ophthalmology

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Ischemic retinal vasculitis is an inflammation of retinal blood vessels associated with vascular occlusion and subsequent retinal hypoperfusion. It can cause visual loss secondary to macular ischemia, macular edema, and neovascularization leading to vitreous hemorrhage, fibrovascular proliferation, and tractional retinal detachment. Ischemic retinal vasculitis can be idiopathic or secondary to systemic disease such as in Behçet's disease, sarcoidosis, tuberculosis, multiple sclerosis, and systemic lupus erythematosus. Corticosteroids with or without immunosuppressive medication are the mainstay treatment in retinal vasculitis together with laser photocoagulation of retinal ischemic areas. Intravitreal injections of bevacizumab are used to treat neovascularization secondary to systemic lupus erythematosus but should be timed with retinal laser photocoagulation to prevent further progression of retinal ischemia. Antitumor necrosis factor agents have shown promising results in controlling refractory retinal vasculitis excluding multiple sclerosis. Interferon has been useful to control inflammation and induce neovascular regression in retinal vasculitis secondary to Behçet's disease and multiple sclerosis. The long term effect of these management strategies in preventing the progression of retinal ischemia and preserving vision is not well understood and needs to be further studied.

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“… 7 , 8 Particularly, Falavarjani et al. reported a case of unilateral CRAO with cilioretinal artery sparing and optic nerve atrophy in a 9-year-old boy 9 , 10 . Unilateral branch retinal artery occlusion (BRAO) and non-ischemic central retinal vein occlusion were also reported.…”

Section: Discussionmentioning

confidence: 99%

“…Unilateral branch retinal artery occlusion (BRAO) and non-ischemic central retinal vein occlusion were also reported. 7 , 8 , 9 , 10 Interestingly, Saatci et al. reported a case of unilateral retinal vasculitis with a BRAO that required laser panretinal photocoagulation for neovascularization.…”

Section: Discussionmentioning

confidence: 99%

Simultaneous central retinal artery occlusion and optic nerve vasculitis in Crohn disease

Coussa

Ali-Ridha

Vilà

et al. 2017

American Journal of Ophthalmology Case Reports

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PurposeTo describe a case of Crohn disease presenting as occlusive vasculitis resulting in a central retinal artery occlusion (CRAO) in one eye and transient ischemic optic neuropathy in the fellow eye.ObservationsAn 18-year-old patient recently diagnosed with biopsy-proven Crohn disease presented with CRAO OD after a previous episode of transient visual loss OS. Extensive workup was negative for other autoimmune or infectious etiologies. The patient was started on intravenous methylprednisolone for 72 h followed by maintenance dose of azathioprine and oral prednisone. Signs of inflammation resolved gradually with some improvement of visual acuity despite developing optic atrophy.Conclusions and importanceTo our knowledge, this is the first case of unilateral CRAO and bilateral optic nerve occlusive vasculitis in Crohn disease, which should be considered as an etiology of retinal vascular occlusive disorders especially in young patients. It is important for ophthalmologists to be aware of the ophthalmic risks associated with Crohn disease as aggressive treatment with systemic steroids and immunosuppressive agents is often needed.

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Central retinal artery occlusion in Crohn disease

Cited by 15 publications

References 7 publications

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Neurological manifestations related to Crohn’s disease: a boon for the workforce

Ischemic Retinal Vasculitis and Its Management

Simultaneous central retinal artery occlusion and optic nerve vasculitis in Crohn disease

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