Central Retinal Artery Occlusion: Can We Effectively Manage This Ocular Emergency in a Hospital Setting?

Jayasinghe, Maleesha; Prathiraja, Omesh; Kayani, Abdul Mueez Alam; Jena, Rahul; Singhal, Malay; Silva, Minollie Suzanne

doi:10.7759/cureus.27840

Cited by 2 publications

(1 citation statement)

References 19 publications

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“…In a paper titled "Central Retinal Artery Occlusion: Can We Effectively Manage This Ocular Emergency in a Hospital Setting?" Jayasinghe et al suggested, "Current data mandates that CRAO should be treated with the same urgency as an acute ischemic cerebral stroke"; however, regarding IVT states, "Treatments other than intra-arterial and intravenous thrombolysis have shown some improvement in the management of CRAO when provided as combination therapy" and "...it is crucial to conduct additional clinical trials on CRAO patients to identify the optimal combination of drugs required for optimal results in CRAO" [29]. A review by Madike et al recommended, "If the patient's vision loss has been less than 4.5 h, IV tPA should be considered in collaboration with the stroke team.…”

Section: Literature Overviewmentioning

confidence: 99%

Intravenous Thrombolysis for Central Retinal Artery Occlusion: A Look at the Literature for the Emergency Medicine Physician

Webb¹

2023

Cureus

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Central retinal artery occlusion (CRAO) is a subtype of ischemic stroke and true ocular emergency presenting with acute, painless, monocular vision loss. Typical findings include poor visual acuity (VA), impaired color vision, relative afferent pupillary defect, and on fundoscopic evaluation, retinal edema, cherry red spot, and occasionally visualization of retinal artery emboli. While there are no proven treatments for CRAO, options include orbital massage, hyperbaric oxygen therapy, and intra-arterial or intravenous thrombolysis (IVT). This study reviews the current literature on the efficacy of IVT for patients affected by acute, symptomatic CRAO and provides an up-to-date, evidence-based background for emergency physicians (EPs) who evaluate and manage these patients.

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Section: Literature Overviewmentioning

confidence: 99%

Intravenous Thrombolysis for Central Retinal Artery Occlusion: A Look at the Literature for the Emergency Medicine Physician

Webb¹

2023

Cureus

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A Review of Current Literature on Central Retinal Artery Occlusion: Its Pathogenesis, Clinical Management, and Treatment

Tiwari,

Bagga,

Prasad

et al. 2024

Cureus

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The ocular analogue of a cerebral stroke is central retinal artery occlusion (CRAO), a medical emergency concerning the eyes. Most patients experience substantial acute vision loss with a visual acuity of 20/400 or worse, resulting in decreased quality of life (QoL) and decreased functional ability. An impending cerebral stroke and ischemic heart disease are also more likely. The four distinct clinical entities that make up CRAO are non-arteritic CRAO, transitory non-arteritic CRAO, non-arteritic CRAO with cilioretinal artery sparing, and arteritic CRAO. Depending on the CRAO type, clinical traits, visual results, and treatment all vary greatly. Contrary to current belief, there is a spontaneous improvement in the optical field and vision, mainly in the first week. The likelihood of instinctive development in optical acuity in the first seven days varies greatly. The pathogenesis, epidemiology, and medical features of CRAO will be described in this review, along with present and potential management future options.

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Central Retinal Artery Occlusion: Can We Effectively Manage This Ocular Emergency in a Hospital Setting?

Cited by 2 publications

References 19 publications

Intravenous Thrombolysis for Central Retinal Artery Occlusion: A Look at the Literature for the Emergency Medicine Physician

Intravenous Thrombolysis for Central Retinal Artery Occlusion: A Look at the Literature for the Emergency Medicine Physician

A Review of Current Literature on Central Retinal Artery Occlusion: Its Pathogenesis, Clinical Management, and Treatment

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