Central Mucoepidermoid carcinoma: case report, literature review for missing and available information and guideline proposal for coming case reports

Central Mucoepidermoid Carcinoma, A Case Report with Molecular Analysis of the TORC1/MAML2 Gene Fusion

“…The prognosis of patients with intraosseous MEC is good [2,7], especially for patients with radiologically cystic or rarefying type lesion [8]. Our patient follow up and outcome are in agreement with these findings.…”

“…Their intraosseous development is rare and not infrequently associated with early diagnostic and management difficulties [2]. The histogenesis of intraosseous MEC is uncertain, but an origin from ectopic salivary tissue or metaplastic transformation of odontogenic epithelium has been proposed [3][4][5].…”

“…Case reports and review articles of such an occurrence show that they typically present at relatively young age, more in female than male patients, with the most common symptoms being pain and swelling [2,3,[5][6][7]. Radiologically, these lesions show unilocular or multilocular wellcircumscribed radiolucency, though variable radiological patterns have been reported [8].…”

“…Radiologically, these lesions show unilocular or multilocular wellcircumscribed radiolucency, though variable radiological patterns have been reported [8]. Histopathologically, tumors manifest cystic formation with conventional features of low to intermediate grade features [2,8].…”

Primary intraosseous mucoepidermoid carcinoma of the maxilla

“…[7][8][9][10][11] Low grade mucoepidermoid carcinoma is treated surgically with local wide block, while the high grade tumours require wide block excision with radical neck dissection. Radiotherapy and chemotherapy are generally reserved for selected cases because of the long term adverse effects.…”