Central calcifying epithelial odontogenic tumour in the posterior maxilla: a case report

Abstract

The calcifying epithelial odontogenic tumour (CEOT), or Pindborg tumour, is a rare, benign odontogenic tumour. CEOT is usually asymptomatic and an incidental radiological finding, often presenting as a mandibular radiolucency with flecks of calcific material. We report an unusual case of CEOT in the left posterior maxilla of a 46-year-old male that was associated with an unerupted tooth. The tumour in this case caused non-specific sinus symptoms and appeared radiographically similar to an odontoma or ossifying fibroma due to its dense calcific contents. Diagnosis was confirmed histologically following surgical removal of the lesion, which showed classic CEOT histomorphology. We report this case to highlight the unusual clinico-radiologic presentation and illustrate the diagnostic difficulties that can occur with radiolucent and/or radiopaque lesions in the jaws.Keywords: Calcifying epithelial odontogenic tumour, cone beam computed tomography, jaw radiolucency, jaw radiopacity, Pindborg tumour.Abbreviations and acronyms: AOT = adenomatoid odontogenic tumour; CBCT = cone beam computed tomography; CCOT = calcifying cystic odontogenic tumour; CEOT = calcifying epithelial odontogenic tumour; COF = central ossifying fibroma; CT = conventional computed tomography; FOV = field of view.

An Aggressive Calcifying Epithelial Odontogenic Tumor: A Rare Case Report

“…Although the case also reported in maxilla but less frequent as compared to mandible [10]. The further central intraosseous form is the most common, larger, and more invasive [11] and about 50% of cases show signs of cortical plate perforation [12]. A study conducted by Bruno R. et al according to results the distribution of 247 cases of CEOT among different ethnic groups/races is as follows white-90, Asian-55, Indian -54, blacks -29, Hispanics-8, Persian/Iranian -6, and 5 in Turkish [12].…”

“…In the CT Scan, the expansion of buccal and lingual cortical plates, its thinning, and discontinuation due to breakage is seen clearly [4].CBCT scans may also help in evaluating the true lesion size, the pattern of growth, the presence of calcifications, and the relationship to adjacent structures. It provides a threedimensional assessment of lesion with higher resolution in relatively low radiation dose [11].…”

Central Osteoma of Maxilla Associated with an Impacted Tooth: Report of a Rare Case with Literature Review

“…Differential diagnosis of the lesion in the present case include complex odontoma, central ossifying fibroma, osteoid osteoma, osteblastoma, Pindborg's tumor and low grade osteosarcoma ( Table 2). [20,21] Osteoblastoma [22][23][24] Central ossifying fibroma [22][23][24] Calcifying epithelial odontogenic tumor [25,26] Osteosarcoma [27][28][29][30] Odontomas are hamartomas of hard tissue of dental origin with most of them arising in the second to third decade of life. Compound odontomes usually develop in the earlier age group than the complex odontomes.…”

“…The margins are usually well defined. Histologically, the tumor comprises of polyhedral epithelial cells arranged in sheets in a fibrous background, Liesegang's rings and variable amount of amyloid like material [26].…”

Unusual case report of an adenomatoid odontogenic tumor in the mandible: 3-years of follow-up

“…Moreover, no dental resorption was observed (Figure 3). Based on CBCT sections, the main diagnoses changed to a mixed profile lesion and included AOT, calcifying epithelial odontogenic tumor and calcifying odontogenic cyst 18,19,20,21 . Legal guardians signed informed consent regarding publishing their data and photographs.…”