2009
DOI: 10.1590/s1516-84842009005000031
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Células-tronco de medula óssea em isquemia crítica de membros

Abstract: Os autores discutem aspectos clínicos e de tratamento convencional da isquemia critica dos membros inferiores e consideram a possibilidade de tratamento com células-tronco autógenas de medula óssea para os pacientes que já esgotaram, sem sucesso, todos os meios de tratamento conhecidos. Comentam sobre o histórico, as fontes, as experiências animais e clínicas e, finalmente, apresentam sua experiência inicial com seis pacientes, todos com indicação de amputação maior ou menor. Em apenas um paciente não foi poss… Show more

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Cited by 3 publications
(2 citation statements)
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References 57 publications
(73 reference statements)
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“…Critical lower limb ischemia is the most severe form of PAD and although revascularization is the gold standard treatment, it may not be applicable to all patients (6). In cases where revascularization is not possible, other treatment methods, such as analgesics, vasodilators, and anticoagulants, can relieve pain at rest and avoid amputations (7,8). Lumbar sympathetic block (LSB) is recommended in the case of persistent pain (9,10).…”
Section: Introductionmentioning
confidence: 99%
“…Critical lower limb ischemia is the most severe form of PAD and although revascularization is the gold standard treatment, it may not be applicable to all patients (6). In cases where revascularization is not possible, other treatment methods, such as analgesics, vasodilators, and anticoagulants, can relieve pain at rest and avoid amputations (7,8). Lumbar sympathetic block (LSB) is recommended in the case of persistent pain (9,10).…”
Section: Introductionmentioning
confidence: 99%
“…4 The recommended treatment aims to relieve symptoms and consists of the use of analgesics, prostaglandins and stem cells, the latter two remain experimental. 5 , 6 In case of refractory pain, lumbar sympathectomy is recommended. The aim of this article is to report the case of a patient with CLI, successfully treated with neurolitic block of the lumbar sympathetic chain, and perform a systematic review of lumbar sympathectomy as CLI treatment.…”
Section: Introductionmentioning
confidence: 99%