Cellulose and Its Derivatives Use in the Pharmaceutical Compounding Practice

Marques-Marinho, Flávia Dias; Vianna-Soares, Cristina Duarte

doi:10.5772/56637

Cited by 26 publications

(10 citation statements)

References 63 publications

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“…There are many excipients derived from cellulose used in drug preparations that improve manufacturing processes, decrease costs and improve the performance of medicine. Different modification methods have been investigated and developed to create more favorable cellulose-based excipients (Dias and Duarte 2013). Specific polymers can be used to control the release of active pharmaceutical ingredients (API) in constant doses over long periods, increase the stability of the API by entrapping it within the matrix of a polymer, tuning the release of both hydrophilic and hydrophobic drugs through swelling, and eroding the nature of the polymers (Godwin et al 2001;Kim et al 2008).…”

Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite

et al. 2019

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In this study, a magnetically enhanced drug delivery composite was synthesized by coprecipitating magnetite nanoparticle (MNP) with 2,3-dialdehyde cellulose-6-phosphate (DACP) and investigated for ampyrone drug loading and controlled delivery. The magnetic core containing Fe 3 O 4 was synthesized through the intramolecular Cannizzaro reaction during the in situ preparation of MNPs in the presence of sodium hydroxide solution, producing hydroxyl acid cellulose phosphate (HACP). The prepared magnetite nanocomposite MNP/HACP was characterized using FT-IR, SEM-EDX, XRD, TEM, VSM and TGA. The release profiles of ampyrone loaded on MNP/HACP showed a continuous release rate of more than 95% after 50 h, compared to the lower release rate of DACP, where only 60% of the loaded ampyrone was released after 50 h. These results show that MNP/HACP nanocomposites present an enhanced loading-release system with the potential to act as a magnetically enhanced drug delivery system.

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Section: Introductionmentioning

confidence: 99%

Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite

et al. 2019

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“…Cellulose derivatives like cellulose acetate, CAB, hydroxypropyl methylcellulose phthalate, methyl cellulose, ethyl cellulose, hydroxyl ethyl cellulose, carboxymethyl cellulose, sodium carboxymethyl cellulose, hydroxyl ethyl cellulose, and hydroxyl propyl methyl cellulose can also be used for hydrogel preparation. These hydrogels have various applications in the field of biomedical engineering, development of sensors, healthcare and hygiene products, agriculture improvement, etc 126–130 …”

Section: Extraction Of Cellulose From Plantsmentioning

confidence: 99%

Extraction processes for deriving cellulose: A comprehensive review on green approaches

Khan

Jolly

Fatima

et al. 2022

Polymers for Advanced Techs

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Cellulose is a renewable, biodegradable and thermally stable compound with several other strong and attractive properties. Cellulose being most abundant raw material on earth has been also produced commercially through several plants every year because of its substantial involvement in variety of potential applications. Cellulose and its derivatives can be employed in paper, textile industry, and food industry along with its utilization in pharmaceutical and biomedical applications. Such applications entail the extraction process in order to obtain an appropriate form of cellulose as required for its utilization in respective applications. Herein, we present a review that focus on the multiple methodology for cellulose extraction from various sources of plants and agricultural waste.

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“… Structure of cellulose with the carbon atoms numbered, showing the repeating cellobiose unit in cellulose (adapted and modified from Marinho [ 53 ]). …”

Section: Figurementioning

confidence: 99%

Lignocellulosic Biomass-Derived Nanocellulose Crystals as Fillers in Membranes for Water and Wastewater Treatment: A Review

et al. 2022

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The improvement of membrane applications for wastewater treatment has been a focal point of research in recent times, with a wide variety of efforts being made to enhance the performance, integrity and environmental friendliness of the existing membrane materials. Cellulose nanocrystals (CNCs) are sustainable nanomaterials derived from microorganisms and plants with promising potential in wastewater treatment. Cellulose nanomaterials offer a satisfactory alternative to other environmentally harmful nanomaterials. However, only a few review articles on this important field are available in the open literature, especially in membrane applications for wastewater treatment. This review briefly highlights the circular economy of waste lignocellulosic biomass and the isolation of CNCs from waste lignocellulosic biomass for membrane applications. The surface chemical functionalization technique for the preparation of CNC-based materials with the desired functional groups and properties is outlined. Recent uses of CNC-based materials in membrane applications for wastewater treatment are presented. In addition, the assessment of the environmental impacts of CNCs, cellulose extraction, the production techniques of cellulose products, cellulose product utilization, and their end-of-life disposal are briefly discussed. Furthermore, the challenges and prospects for the development of CNC from waste biomass for application in wastewater treatment are discussed extensively. Finally, this review unraveled some important perceptions on the prospects of CNC-based materials, especially in membrane applications for the treatment of wastewater.

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Cellulose and Its Derivatives Use in the Pharmaceutical Compounding Practice

Cited by 26 publications

References 63 publications

Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite

Synthesis, characterization and ampyrone drug release behavior of magnetite nanoparticle/2,3-dialdehyde cellulose-6-phosphate composite

Extraction processes for deriving cellulose: A comprehensive review on green approaches

Lignocellulosic Biomass-Derived Nanocellulose Crystals as Fillers in Membranes for Water and Wastewater Treatment: A Review

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