Cellulitis due to Streptococcus pneumoniae with Diminished Susceptibility to Penicillin in an Immunocompromised Patient

Souweine, Bertrand; Mom, T.; Bret, Laurent; Klisnick, A; Baguet, J. C.; Gilain, L.

doi:10.3109/00365549709011867

Cited by 13 publications

(3 citation statements)

References 7 publications

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“…L'hyperleucocytose à polynucléaires neutrophiles est classique. La diminution de la CRP serait plus précoce en cas d'évolution favorable (7). La flore anaérobie à l'état physiologique est saprophyte de la cavité buccale et de l'oropharynx (8).…”

Section: Discussionunclassified

Les cellulites cervico-faciales d’origine dentaire: a propos de 150 cas

Benzarti¹,

Mardassi²,

Mhamed³

et al. 2010

Journal Tunisien d'ORL Et De Chirurgie Cervico-Faciale

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Section: Discussionunclassified

Les cellulites cervico-faciales d’origine dentaire: a propos de 150 cas

Benzarti¹,

Mardassi²,

Mhamed³

et al. 2010

Journal Tunisien d'ORL Et De Chirurgie Cervico-Faciale

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“…S. Pneumoniae cellulitis is usually treated with Penicillin. The emergence of drug-resistant pathogen has made the treatment more challenging especially in patients who are immunocompromised [12].…”

Section: Discussionmentioning

confidence: 99%

Pneumococcus a Rare Cause of Cellulitis

Asghar¹,

Kommineni²,

Mehta³

et al. 2018

AJMCR

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Streptococcus Pneumoniae (S. pneumoniae) is a common cause of community-acquired pneumonia, although its manifestation as a skin infection is a rare phenomenon. Most skin infections are secondary to Staphylococcus aureus or Streptococcus pyogenes, however, cellulitis caused by pneumococci is an infrequent finding. Pneumococcal cellulitis most often occurs due to bacteremia in patients with chronic illnesses such as diabetes, underlying malignancies, immunosuppressed patients, and patients with the history of injection drug abuse. The nature of the infection can be very fatal leading to fasciitis, myonecrosis, septic shock and ultimately death. We present a case of a 61-year-old female who developed painful swelling and redness of the right face along with bilateral leg involvement. In the emergency room, physical examination revealed multiple cervical lymphadenopathies. Further diagnostic investigations disclosed Low-grade B-cell non-Hodgkin lymphoma upon cervical lymph node biopsy. Blood culture grew Streptococcus pneumoniae as a source of cellulitis. This case demonstrates the importance of immune defects and the ensuing development of pneumococcal-induced cellulitis. Physicians should be vigilant while treating Pneumococcal cellulitis as this may be a sign of the serious underlying medical condition.

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“…Diagnosis requires the demonstration of the pathogen in culture either from purulent material of cellulitis positive in 86% of cases or from blood cultures positive in 96% in the review by Parada and Maslow, highlighting the importance of obtaining blood cultures 2 . Treatment of pneumococcal cellulitis relies on penicillin, but cellulitis was the result of a penicillin‐resistant strain in two cases 5,15 . Surgical treatment was required in 50% of patients because of suppurative complications with debridement, fasciectomy, amputation and skin graft 2,3 .…”

Section: Discussionmentioning

confidence: 99%