Cellular variant of benign fibrous histiocytoma: A case report

Vaidya, Kuladeepa Ananda; Nagaraj, Tejavathy

doi:10.21276/apjhs.2014.1.4.34

Cited by 1 publication

(4 citation statements)

References 10 publications

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“…[4] Regular follow up is must owing to its high recurrence rate. 9 The present case showed similar microscopic features with positive immunoreactivity for SMA & CD68 demonstrating the lesion to be composed of fibroblastic & histiocytic cells. Negativity for S100 ruled out neurogenic tumors & less than 10 % positivity for Ki67 demonstrated the less aggressive behavior.…”

Section: Discussionsupporting

confidence: 75%

“…[1] In addition Han et al classified it as fibrocollagenous, histiocytic, cellular, aneurysmal, angiomatous, sclerotic, monster, palisading & keloidal types. [9] Amongst all these cellular variant is found to have most aggressive behavior & high risk of local recurrence (25%) & often poses a diagnostic challenge to distinguish it from more aggressive lesions such as fibrosarcoma. [9] Prominent fascicular or storiform pattern of fibroblasts in the present case was consistant with the cellular variant of BFH.…”

Section: Discussionmentioning

confidence: 99%

“…[9] Amongst all these cellular variant is found to have most aggressive behavior & high risk of local recurrence (25%) & often poses a diagnostic challenge to distinguish it from more aggressive lesions such as fibrosarcoma. [9] Prominent fascicular or storiform pattern of fibroblasts in the present case was consistant with the cellular variant of BFH. Because of its high recurrence rate regular 1 year follow up was advised to the patient.…”

Section: Discussionmentioning

confidence: 99%

“…Because of its high recurrence rate regular 1 year follow up was advised to the patient. 9 The differential diagnosis of oral BFH includes MFH, fibrosarcoma, solitary fibrous tumor, angiomatoid fibroushistiocytoma & leiomyoma.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Benign Fibrous Histiocytoma of Mandible: A Pathogenetic & Diagnostic Perspective

Salve¹,

Bhavthankar²,

Mandale³

2016

IOSR

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Fibrous histiocytoma is a heterogenous group of mesenchymal tumors that is primarily composed of fibroblasts & histiocytes. The most common site of occurrence of these lesions is on the skin of extremities. Intraoral benign fibrous histiocytomas (BFH)s are commonly seen in the soft tissues of the buccal mucosa, gingiva, lips, soft palate & floor of the mouth. However its occurrence in deeper soft tissues (less than 1%) & intrabony locations is not unusual. Jaw bones are found to be the rarest sites, as till date only two cases in maxilla & six in mandible have been reported. Also BFH represents a pathologist's phantasm because histologically & morphologically it mimics many other soft tissue tumors. Because of lack of presence of specific immunohistochemical marker for BFH, diagnosis is confirmed on exclusion basis. A case of BFH at an unusual location-mandibular paraosteum is reported here along with its pathogenetic & diagnostic perspective.

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Section: Discussionsupporting

confidence: 75%

Section: Discussionmentioning

confidence: 99%