Cellular Perception: When the Cell Model Includes a Sense Order which Ensues from a Philosophy of Nature, the Signaling and Epigenetics Effects which Can Result from Exposure to Magnetic Fields Are Described Better

Abstract

Academic biology-medicine refers to a couple of philosophies, Organicism and Mechanism, which translates into an association of Cybernetic diagrams and molecular Reductionism. This association presents logical difficulties which make it unsuitable to describe correctly biological effects of electromagnetic fields, EMF. But these logical difficulties may be overcome when renewing the organic cell idea by means of a Philosophy of Nature which juxtaposes causality order and sense order in the cell. The signalsome, the set of descriptive components resulting from the genome, is constantly reorganized. This remodeling may become epigenetic when the phenotype becomes transformed by experience of perceptions in a given medium, because the perception of overall information coming from the extracellular medium becomes functional within the system. In that cellular perception, it is stated that the significance base which contributes to the sense order results from the qualitative topological structure of the extracellular medium. Therefore the EMF interactions target is not only the membrane and its molecules; it is also the structure of the extracellular medium which bathes the membrane. Knowing that the sense order modulation constitutes the global soil of the (localized) causality order, it is possible to obtain a same EMF bioeffect on a membrane molecule by treating a culture of cells in its bath or by treating only the extracellular aqueous medium. Consequently, the double bioeffect resulting from EMF exposure is described simply, because the sense order, such as it results from the qualitative structuring of the medium, forms the significance base which directs the causal mechanics of the cellular answer

Understanding the Feedback Loops between Energy, Matter and Life

“…To close this loop, resting potential differences induced by membrane changes can also be propagated, for example by cell-to-cell GJ transfers. Some workers have described a rich EMF world in the interior of the cell [15,99]. However, only a few facts are available to build a comprehensive scientific understanding.…”

Cellular Psychology Assumption: Based upon Exterior Algebra, It Contributes to Explaining the Variability of the Bioeffects of Magnetic and Electromagnetic Fields

“…In a similar way, Nature Philosophy considers that any living organism is defined through a total shape. It is a set of virtual possibilities of which only one may become real under specific medium and state conditions [10]. Thus the organism could have an imaginary function of each of its possible conformations when confronted with a forthcoming reality.…”

“…That is why the law of Fechner-Weber does not apply in energetics-including when it concerns the sense of a physiopathological pain that the patient can evaluate on a visual analogical scale, VAS, of 10 cm. 10 Theories relating to the mind-body relation go back to Aristotle who considered that there are two aspects of the same entity, unlike Descartes who regarded mind and body as separate, and Leibniz who believed in separated aspects, but with processes equipped with parallels. Evaluations of the mind-body relation by experimental psychology hardly contribute to the explanation when using the causal law of Fechner-Weber.…”

“…The method which allows it is said to have been invented by a man named Tartaglia, (the Stammerer) 12 The concept of being-envelope of the organism is an essential asset of the philosophy of Nature. A broad description was given by Le Chapellier, (2011, [10]), around the four following points: 1) The concept of a simple or complex organism allows the Cartesian aporia, to be overcome (see n.3): to logically suture the tear of Nature opened by Cartesian dualism, the mathematician A. N. Whitehead, (1925, [42]), stated that every natural being has an organism and that any organism presents properties of endurance, stability, and extension.…”

“…Insofar as the most elementary psychic material is the feeling, cells have probably a psychic part which is an elementary material unconscious. This way, the evolutionary change under dictation of a repeated event, is not done without a natural attempt to get back to the previous order, because material unconscious is former to the present cell status with its molecules organization [10]. In that way, topological nuances which integrated the being-envelope during PEMF treatment meet consist of a temporal thickness.…”