Cellular blue nevus of the vulva mimicking Bartholin’s gland abscess in a 15-year-old girl: a case report

Abstract

CBN should be considered in the differential diagnosis of vulvar masses in adolescent period.

A Scoping Review and Population Study Regarding Prevalence and Histopathology of Juvenile Vulvar Melanocytic Lesions. A Recommendation

“…Case reports of vulvar naevi in juveniles other than melanomas. We found 15 case-reports (Bussen, 2009, Hoffmann et al, 2011, Lebeau et al, 2006, Mandal et al, 2009, Mulcahy et al, 2013, Neri et al, 2016, Pinto et al, 2012, Polat et al, 2009, Quint and Trager, 2004, Rotunno et al, 2019, Schaffer et al, 2005, Spatz et al, 1998, Tan et al, 2020, Yamazhan et al, 2012, Zhou and Crowson, 2003 of non-melanoma vulvar melanocytic lesions in juveniles, ages 6-18, illustrating diagnostic pitfalls especially with concomitant LS. Pinto (Pinto et al, 2012) discuss the possible role of VLS in malignant transformation of melanocytes, analogous to the risk of vulvar squamous cell carcinoma (VSCC) seen with a background of LS.…”

“…We found 15 case reports ( Bussen, 2009 ; Hoffmann et al., 2011 ; Lebeau et al., 2006 ; Mandal et al., 2009 ; Mulcahy et al., 2013 ; Neri et al., 2016 ; Pinto et al., 2012 ; Polat et al., 2009 ; Rotunno et al., 2019 ; Schaffer and Orlow, 2005 ; Spatz et al., 1998 ; Tan et al., 2020 ; Trager, 2004 ; Yamazhan et al., 2012 ; Zhou and Crowson, 2003 ) of nonmelanoma vulvar melanocytic lesions in juveniles, ages 6‒18 years, illustrating diagnostic pitfalls, especially with concomitant LS. Pinto et al.…”

“… Spatz et al. (1998) Vulvar blue nevus Case report 1 case, age 12 No Case report of malignant vulvar blue nevus: nodule seen at age 12 years, malignant blue nevus at age 28 years, and malignant ovarian metastasis at age 43 years, 15 years after removal and diagnosis of malignant blue nevus Tan et al., 2020 Balloon cell vulvar nevus, a melanocytic lesion Case report 1 case, age 15 No Mild cellular and nuclear atypia seen; discuss the diagnosis of balloon cell nevus Trager, 2004 (Congenital) vulvar nevus Case report and review 1 case, age 3 No Rarity of MVM, give advice on how to follow congenital nevus Yamazhan et al., 2012 Vulvar cellular blue nevus in adolescent Case report 1 case, age 15 No Description of case and differential diagnosis Zhou and Crowson, 2003 Milk line nevus Case report 1 case, age 17 No Describe histological features of atypical milk line nevus with; discuss phenomenon of Pagetoid spread and nesting Case serie nonmelanomas Carlson et al., 1997 Differential diagnosis melanoma and nevi Letter n.r. n.r.…”

“…On the other hand, they note that pseudomalignant melanocytic changes are a phenomenon in inflammatory conditions. Single cases of rare types of nevi were reported ( Polat et al., 2009 ; Rotunno et al., 2019 ; Spatz et al., 1998 ; Tan et al., 2020 ; Yamazhan et al., 2012 ).…”

Uterine Cellular Blue Nevus Arising in Mullerian and Pelvic Dendritic Melanocytosis: Case Report of a Rare Phenomenon to Be Distinguished From Uterine Melanoma

“…Malignant blue nevus or blue nevus-like melanoma may arise in pre-existing dendritic melanocytoses, including congenital forms. Benign blue nevi of all subtypes in the female urogenital tract are quite rare, though they have been reported in the endometrium (1,2), endocervix (2)(3)(4), myometrium (5,6), vagina (4,7), and vulva (8). Most of these cases were incidental findings.…”