Cellobiose quinone oxidoreductase from the white rot fungus Phanerochaete chrysosporium is produced by intracellular proteolysis of cellobiose dehydrogenase

Raíces, Manuel; Montesino, Raquel; Cremata, José A.; Garcı́a, Bianca; Perdomo, Walmer; Szabó, I.; Henriksson, Gunnar; Hållberg, Bengt; Pettersson, Göran; Johansson, Gunnar

doi:10.1016/s0167-4781(02)00243-9

Cited by 16 publications

(16 citation statements)

References 30 publications

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“…CDH and CBQ had similar amino acid sequences. [13][14][15] Hence CDH and CBQ are generally classified into the same group. Since there is no homology in amino acid sequence between the former group (COX and GOOX) and the latter (CBQ and CDH), we propose a new classification that divides the enzymes into two groups: the COX and GOOX to COX group, and the CDH and CBQ to CDH groups.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Purification and Characterization of a Carbohydrate:Acceptor Oxidoreductase fromParaconiothyriumsp. That Produces Lactobionic Acid Efficiently

Kiryu

Nakano

Kiso

et al. 2008

Bioscience, Biotechnology, and Biochemistry

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Section: Discussionmentioning

confidence: 99%

“…COX and GOOX show no sequence homology to CBQ or CDH, whereas the amino acid sequences of CBQ and CDH are similar. 10,[12][13][14][15] These results indicate that COX and GOOX are different enzymes from CBQ and CDH, and that CBQ and CDH belong to the same group. On the other hand, no homology between COX and GOOX has been proposed.…”

mentioning

confidence: 85%

Purification and Characterization of a Carbohydrate:Acceptor Oxidoreductase fromParaconiothyriumsp. That Produces Lactobionic Acid Efficiently

Kiryu

Nakano

Kiso

et al. 2008

Bioscience, Biotechnology, and Biochemistry

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“…Then this free flavin domain of CDH is called cellobiose: quinone oxidoreductase (CBQ), a member of extracellular redox enzymes (Fig. 1C) (Raíces et al, 2002). It has been thought that CBQ is only generated from CDH by proteolysis (Raíces et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

“…1C) (Raíces et al, 2002). It has been thought that CBQ is only generated from CDH by proteolysis (Raíces et al, 2002).…”

Section: Introductionmentioning

confidence: 99%

FCD1 encoding protein homologous to cellobiose: Quinone oxidoreductase in Fusarium oxysporum

Kawabe

Yoshida

Teraoka

et al. 2006

Gene

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“…Some enzymes have been known to oxidize lactose. Such enzymes, cellobiose dehydrogenases (EC 1.1.99.18, CDH), 7,8) cellobiose: quinone oxidoreductases (EC 1.1.5.1, CBQ), 9,10) glucooligosaccharides oxidases (GOOX), 11,12) and carbohydrate: acceptor oxidoreductase (COX), 13) however, have not been studied from a viewpoint of calcium lactobionate production in detail. This may be due to their instability at acidic pH, and or low specificity on O2 as an electron acceptor.…”

mentioning

confidence: 99%

Production of Calcium Lactobionate by a Lactose-oxidizing Enzyme from <i>Paraconiothyrium</i> sp. KD-3

et al. 2008

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A lactose-oxidizing enzyme was obtained from culture supernatant of a fungal strain of Paraconiothyrium sp. KD-3. The enzyme was a flavoprotein with a molecular mass of 54 kDa. The purified enzyme oxidized various monosaccharides and oligosaccharides such as D-glucose, D-galactose, D-xylose, cellooligosaccharides and maltooligosaccharides in addition to lactose, using molecular oxygen as a good electron acceptor, to accumulate the corresponding aldonic acids and hydrogen peroxide. The Paraconiothyrium enzyme was suitable for the production of calcium lactobionate compared with a commercial hexose oxidase owing to the stability during the conversion. The enzyme converted 10 20% (w v) lactose completely to calcium lactobionate in a 500-mL reactor under aeration, agitation and pH regulation at 5.5. The neutralization was successfully performed by the addition of 10% (w w) slurry of calcium carbonate, while neutralization with 25% (w v) sodium hydroxide solution inactivated the enzyme gradually. The supplement of catalase to the mixture promoted the conversion by degrading hydrogen peroxide. The immobilized enzyme, which was prepared by the adsorption to a cation exchange resin followed by the condensation with carbodiimide, oxidized 18.5% (w v) lactose to produce calcium lactobionate in a batch reaction. Calcium lactobionate and aldonates derived from D galactose, D-xylose and L-arabinose showed high aqueous solubility and low calcium binding capability.

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Cellobiose quinone oxidoreductase from the white rot fungus Phanerochaete chrysosporium is produced by intracellular proteolysis of cellobiose dehydrogenase

Cited by 16 publications

References 30 publications

Purification and Characterization of a Carbohydrate:Acceptor Oxidoreductase fromParaconiothyriumsp. That Produces Lactobionic Acid Efficiently

Purification and Characterization of a Carbohydrate:Acceptor Oxidoreductase fromParaconiothyriumsp. That Produces Lactobionic Acid Efficiently

FCD1 encoding protein homologous to cellobiose: Quinone oxidoreductase in Fusarium oxysporum

Production of Calcium Lactobionate by a Lactose-oxidizing Enzyme from <i>Paraconiothyrium</i> sp. KD-3

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