“…This was one reason why L1, TAG-1, and SC-1 were selected for tests of CAM synthesis by axon-regenerating rat RGCs. Moreover, related proteins and direct homologs in various species have been demonstrated to be involved in axon elongation, recognition, fasciculation, and contact stabilization (i.e., TAG-1 in mouse: Furley et al, 1990; axonin-1 in chick: Ruegg et al, 1989;Stoeckli et al, 1991; L1 in mouse and rat: Bartsch et al, 1989;Mohajeri et al, 1996;; NgCAM in chick: Lemmon et al, 1989;Chang et al, 1987;Rathjen et al, 1987;Yamagata et al, 1995;E587 antigen in goldfish: Bastmeyer et al, 1995; SC-1/DM-GRASP in chick: Burns et al, 1991;Tanaka et al, 1991;Pollerberg and Mack, 1994;Yamagata et al, 1995;neurolin in goldfish: Bastmeyer et al, 1996). Moreover, CAMs activate signal transduction pathways which effect and modulate axon growth (Doherty and Walsh, 1994;Kunz et al, 1996).…”