Celiac disease

King, A; Ciclitira, Paul J.

doi:10.1097/00001574-200003000-00002

Cited by 4 publications

(5 citation statements)

References 37 publications

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“…23 The immune reaction in celiac disease is towards gluten and similar proteins occurring at the mucosal lining of small intestine causing cytological damage resulting in blunting of villi due to which patient with celiac disease have gastrointestinal symptoms apart from that they have higher rates of type1 diabetes mellitus,o ral infections, recurrent abortions, intrauterine growth restriction and still births. 24 Similarly, another report shows that the rate of spontaneous abortions were 15% in this group and 6% in an unaffected control group. 25 Our case also presented with history of recurrent pregnancy losses.…”

Section: Discussionmentioning

confidence: 51%

Celiac disease and pregnancy in Indian scenario

Verma

Tyagi

Singh

2018

Int J Reprod Contracept Obstet Gynecol

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Celiac disease is a chronic lifelong inflammatory condition of gastrointestinal tract specifically the small intestine. We report a case of pregnancy outcome in a patient with celiac disease (gluten sensitive enteropathy) diagnosed during the investigations of recurrent abortions and intermittent diarrhoea since childhood. A 32 years old patient who had four abortions and loss of a premature baby was diagnosed as celiac disease during investigations of recurrent abortions and diarrhoea since childhood. After stabilisation of disease she conceived spontaneously. Patient had regular follow up in some private institute. She was referred to our hospital as a case of IUGR with color Doppler changes with breech presentation with sluggish fetal movements at 37 weeks and emergency caesarean section was performed. A male fetus with 2.25 kg AS 7, 9 at birth was delivered. The cause of her recurrent pregnancy losses and previous preterm birth was celiac disease. Celiac disease (CD) is an immune-mediated enteropathy caused by a permanent sensitivity to gluten in genetically susceptible individual. It may also lead to serious maternal and fetal complications because of systemic effects of disease however a successful pregnancy outcome is possible when pre-gestational diagnosis is made and proper management of disease during pregnancy is achieved.

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Section: Discussionmentioning

confidence: 51%

Celiac disease and pregnancy in Indian scenario

Verma

Tyagi

Singh

2018

Int J Reprod Contracept Obstet Gynecol

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“…In response to new information regarding the prevalence of undiagnosed CD in Western populations and the benefits of early diagnosis and treatment, some experts are calling for universal screening (King & Ciclitira, 2000). Evidence relating to the role of tTG may lead to the development of noninvasive, reliable test methods that will allow prompt evaluation of patients with suspected CD in the primary care setting in the near future.…”

Section: Resultsmentioning

confidence: 99%

“…It often goes undiagnosed or is misdiagnosed as irritable bowel syndrome (IBS) or lactose intolerance (Voelker, 2000). The potential consequences include increased risk of associated autoimmune diseases, neurological complications, fetal growth retardation where pregnancy precedes diagnosis, and gastrointestinal malignancy (King & Ciclitira, 2000).…”

Section: Implications For Practicementioning

confidence: 99%

“…Celiac disease is of interest to clinicians and scientists because it represents a valuable model for the investigation and comprehension of diseases in which genetic, immunologic, and environmental factors interplay (Branski & Troncone, 1998). Although CD is associated with specific human leukocyte antigen (HLA) class I and class II alleles, other non-HLA linked genetic influences are probably required for development of disease (Ahnen, 2000;King & Ciclitira, 2000).…”

Section: Pathogenesismentioning

confidence: 99%

“…Furthermore, in patients with CD, the risk of developing an autoimmune disorder is related to the duration of gluten exposure (Ventura, Magazzu, & Greco, 1999). CD and DM-1are supported by an identical genetic background of class II HLA genotypes; screening for CD may be justified in patients with newly diagnosed insulin dependence (King & Ciclitira, 2000).…”

Section: Clinical Featuresmentioning

confidence: 99%

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Recognizing and Managing Celiac Disease in Primary Care

Michael¹

2003

Journal of the American Academy of Nurse Practitioners

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Delays in the diagnosis and treatment of CD increase the risk of early mortality, associated autoimmune disease, neurologic complications, gastrointestinal malignancy, and fetal growth retardation, where pregnancy precedes diagnosis. Primary care clinicians must cultivate a high index of suspicion for CD in the primary care setting and bear it in mind as a differential diagnosis in many clinical situations.

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Doença celíaca em um grupo de crianças e adolescentes portadores de diabetes mellitus tipo 1

Brandt

Silva

Antunes

2004

Arq Bras Endocrinol Metab

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To know the prevalence of celiac disease (CD) in a group of children and adolescents with type I diabetes mellitus. A cross sectional study was conducted at the Instituto Materno Infantil de Pernambuco (IMIP) in March 2000. The sample consisted of 19 children and adolescents with type I diabetes mellitus that had the human anti-tissue transglutaminase antibodies assessed using kits from the Eurospital Laboratory. In case of positive results it was realized small intestine biopsy to confirm the diagnosis. For the calculation of the prevalence of CD it was considered the number of patients with serum positive histological alterations of the mucous membrane of the small intestine compatible with CD. Four patients presented serum positivity for human anti-tissue transglutaminase antibodies with a serum prevalence of 21% (4/19). Out of these four subjects, three who accomplished small intestine biopsy presented histological alterations compatible with CD. The prevalence of CD in this group was 15.8% (3/19). The prevalence of CD in this study group was high, suggesting that those with type I diabetes mellitus should be led as a group of high risk to develop this disease.

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Celiac disease

Cited by 4 publications

References 37 publications

Celiac disease and pregnancy in Indian scenario

Celiac disease and pregnancy in Indian scenario

Recognizing and Managing Celiac Disease in Primary Care

Doença celíaca em um grupo de crianças e adolescentes portadores de diabetes mellitus tipo 1

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