CdSe and CdSe/ZnS quantum dots for the detection of C-reactive protein

Abstract

In this study, a method for the detection of C-reactive protein (CRP) using CdSe and CdSe/ZnS quantum dots (QDs) is proposed. CdSe and CdSe/ZnS core-shell QDs are synthesised by using 2-mercaptosuccinic acid (MSA) as a capping agent. These QDs were then subjected to various characterisation studies, namely X-ray diffraction and transmission electron microscope for size and structure, Fourier transform infrared spectroscopy for the confirmation of functional groups, ultraviolet-visible absorption and fluorescence spectroscopy for optical characteristics and dynamic light scattering for hydrodynamic changes of QDs. Two biochemical mixtures were developed: one by mixing blood serum containing CRP and CdSe-phosphorylethanolamine (PEA) and the other by mixing blood serum with CdSe/ZnS-PEA. When these mixtures are observed for fluorescence due to interaction of QDs with CRP, a correlation between changes in fluorescence for different concentrations of CRP is noted. The result demonstrates that CRP can be detected with the help of QDs without using any antibodies.

The Optimized Thickness of Silver Doping on CdS/CdSe for Quantum Dot-Sensitized Solar Cell

“…05-0566 for the cubic phase of ZnS passivation. This result is consistent with that observed in the zinc blende phase [25,26]. Figure 1(f) for the Raman spectrum of the completed QDSSCs with thickness between 1 layer and 4 layers always gives information about the TiO 2 anatase modes at 207.7 cm -1 , 416 cm -1 , and 622 cm -1 positions [27] and the TiO 2 /CdSe:Ag + cubic at 207.7 cm -1 , 270 cm -1 , 416 cm -1 , and 622 cm -1 positions.…”

Structural, Optical and Morphological Characterization of Cdse/Cds Core / Shell Quantum Dots Synthesized via Chemical Bath

“…The size of CdSe/CdS Core/shell QD, from the second figure, was measured to be less than 5nm. The prepared particle diameter(5nm) is consistent with the reported core/shell structure model for the CdSe/CdS sample [25]. This result is in agreement with that of Gadalla et al [18] .…”

“…QDs were spherical based on the Brus model. The quantum confinement energy of the CdSe QDs was obtained from E g(qd) _E bulk which were equal to 0.46 eV and 0.56 Ev, respectively [25].…”

Facile synthesis of crosslinked Cu:ZnS-lignocellulose nanocomposite: a potent antifungal and antisporulant system against the tea pathogen Exobasidium vexans

“…The band observed at 1450 cm -1 corresponds to the aromatic skeletal vibration of the phenolic group of lignin [23, 24] . Also, the characteristic signature for the presence of capping agent SC is represented by the band at 1601 cm -1 which corresponds to the stretching vibration of the citrate group [25] . Fig.…”