CBL1, a Calcium Sensor That Differentially Regulates Salt, Drought, and Cold Responses in Arabidopsis

Cheong, Yong Hwa; Kim, Kyungnam; Pandey, Girdhar K.; Gupta, Rajeev; Grant, John J.; Luan, Sheng

doi:10.1105/tpc.012393

Cited by 387 publications

(316 citation statements)

References 41 publications

(82 reference statements)

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“…The [Ca 2+ ]cyt signatures elicited by one environmental challenge can be modified by prior exposure to a contrasting one (Knight, 2000). Furthermore, transformants obtained via manipulation of one or more components of Ca 2+ signaling pathway were observed to be more tolerant to adverse stress conditions, especially water deficit (Saijo et al, 2000, Pandey et al, 2002, Cheong et al, 2003,, Wang et al, 2005, Liu et al, 2006, Ma et al, 2007.…”

Section: Calcium and Its Rolementioning

confidence: 99%

Genetic approaches towards overcoming water deficit in plants - special emphasis on LEAs

Khurana

Vishnudasan

Chhibbar

2008

Physiol Mol Biol Plants

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Water deficit arises as a result of low temperature, salinity and dehydration, thereby affecting plant growth adversely and making it imperative for plants to surmount such situations by acclimatizing/adapting at various levels. Water deficit stress results in significant changes in gene expression, mediated by interconnected signal transduction pathways that may be triggered by calcium, and regulated via ABA dependent and/or independent pathways. Hence, adaptation of plants to such stresses involves maintaining cellular homeostasis, detoxification of harmful elements and also growth alterations. Stress in general cause excess production of reactive oxygen species (ROS) and the plants overcome the same by either preventing the accumulation of ROS or by eliminating the ROS formed. Ion homeostasis includes processes such as cellular uptake, sequestration and export in conjunction with long distance transport. Requisite amounts of osmolytes are hence synthesized under stress to maintain turgor along with maintaining the macromolecular structures and also for scavenging ROS. Another noteworthy response is the accumulation of novel proteins, including enzymes involved in the biosynthesis of osmoprotectants, heat-shock proteins (HSPs), late embryogenesis abundant (LEA) proteins, antifreeze proteins, chaperones, detoxification enzymes, transcription factors, kinases and phosphatases. The LEAs belong to a redundant protein family and are highly hydrophilic, boiling-soluble, non-globular and therefore have been defined and classified accordingly. The precise function of LEAs is still unknown, but substantial evidence indicates their involvement in dessication tolerance as the expression of LEAs confers increased resistance to stress in heterologous yeast system and also significantly improves water deficit tolerance in transgenic plants. Genetic manipulation of plants towards conferring abiotic stress tolerance is a daunting task, as the abiotic stress tolerance mechanism is highly complex and various strategies have been exploited to address and evaluate the stress tolerance mechanism, and the molecular responses to water deficit via complex signaling networks. Genomic technologies have recently been useful in integrating the multigenicity of the plant stress responses through, transcriptomics, proteomics and metabolite profilling and their interactions. This review deals with the recent developments on genetic approaches for water stress tolerance in plants, with special emphasis on LEAs.

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Section: Calcium and Its Rolementioning

confidence: 99%

Genetic approaches towards overcoming water deficit in plants - special emphasis on LEAs

Khurana

Vishnudasan

Chhibbar

2008

Physiol Mol Biol Plants

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“…These genes included two transcription factor genes, AtERF4 (Fujimoto et al, 2000) and DREB2A (Liu et al, 1998), and four effector protein genes, Cor6.6, Erd10, rd17, and P5CS. The effector protein genes have been used as markers for stressresponse studies (Cheong et al, 2003;Dubouzet et al, 2003). Figure 5A shows that the AtERF4 and Cor6.6 genes were up-regulated by approximately 2.5-to 5.3-fold in the two NTHK1-transgenic lines in comparison to their expression in Col-0 plants under normal condition.…”

Section: Nthk1 Regulates Expressions Of Salt-responsive Genesmentioning

confidence: 99%

Modulation of Ethylene Responses Affects Plant Salt-Stress Responses

et al. 2006

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Ethylene signaling plays important roles in multiple aspects of plant growth and development. Its functions in abiotic stress responses remain largely unknown. Here, we report that alteration of ethylene signaling affected plant salt-stress responses. A type II ethylene receptor homolog gene NTHK1 (Nicotiana tabacum histidine kinase 1) from tobacco (N. tabacum) conferred salt sensitivity in NTHK1-transgenic Arabidopsis (Arabidopsis thaliana) plants as judged from the phenotypic change, the relative electrolyte leakage, and the relative root growth under salt stress. Ethylene precursor 1-aminocyclopropane-1-carboxylic acid suppressed the salt-sensitive phenotype. Analysis of Arabidopsis ethylene receptor gain-of-function mutants further suggests that receptor function may lead to salt-sensitive responses. Mutation of EIN2, a central component in ethylene signaling, also results in salt sensitivity, suggesting that EIN2-mediated signaling is beneficial for plant salt tolerance. Overexpression of the NTHK1 gene or the receptor gain-of-function activated expression of salt-responsive genes AtERF4 and Cor6.6. In addition, the transgene NTHK1 mRNA was accumulated under salt stress, suggesting a posttranscriptional regulatory mechanism. These findings imply that ethylene signaling may be required for plant salt tolerance.

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“…The calcium binding protein CBL1 (calcineurin B-like 1) has been identified as one of these integration points in response to cold, drought, and salt stress (Albrecht et al, 2003;Cheong et al, 2003). Plants overexpressing CBL1 are salt and drought tolerant but freezing sensitive, and loss of CBL1 function makes the plants freezing tolerant and drought and salt sensitive (Albrecht et al, 2003).…”

Section: Rcd1-1 Separates Aba Induction Of Cold Acclimation-related Gmentioning

confidence: 99%

Arabidopsis RADICAL-INDUCED CELL DEATH1 Belongs to the WWE Protein–Protein Interaction Domain Protein Family and Modulates Abscisic Acid, Ethylene, and Methyl Jasmonate Responses

et al. 2004

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Experiments with several Arabidopsis thaliana mutants have revealed a web of interactions between hormonal signaling. Here, we show that the Arabidopsis mutant radical-induced cell death1 (rcd1), although hypersensitive to apoplastic superoxide and ozone, is more resistant to chloroplastic superoxide formation, exhibits reduced sensitivity to abscisic acid, ethylene, and methyl jasmonate, and has altered expression of several hormonally regulated genes. Furthermore, rcd1 has higher stomatal conductance than the wild type. The rcd1-1 mutation was mapped to the gene At1g32230 where it disrupts an intron splice site resulting in a truncated protein. RCD1 belongs to the (ADP-ribosyl)transferase domain-containing subfamily of the WWE protein-protein interaction domain protein family. The results suggest that RCD1 could act as an integrative node in hormonal signaling and in the regulation of several stress-responsive genes.

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CBL1, a Calcium Sensor That Differentially Regulates Salt, Drought, and Cold Responses in Arabidopsis

Cited by 387 publications

References 41 publications

Genetic approaches towards overcoming water deficit in plants - special emphasis on LEAs

Genetic approaches towards overcoming water deficit in plants - special emphasis on LEAs

Modulation of Ethylene Responses Affects Plant Salt-Stress Responses

Arabidopsis RADICAL-INDUCED CELL DEATH1 Belongs to the WWE Protein–Protein Interaction Domain Protein Family and Modulates Abscisic Acid, Ethylene, and Methyl Jasmonate Responses

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