Cavitation-induced drug delivery in tumors for cancer chemotherapy: animal studies

Larina, Irina V.; Bartels, C.; Larin, Kirill V.; Esenaliev, Rinat O.

doi:10.1117/12.434726

Cited by 8 publications

(1 citation statement)

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“…The interaction of ultrasound with the microparticles results in cavitation (formation, growth, and collapse of microbubbles) in tumors without damage to normal tissues. The microparticles serve as cavitation nuclei that substantially lower cavitation threshold selectively in tumors [4][5][6]. The ultrasoundinduced cavitation perforates tumor blood vessel walls and cancer cell membranes and induces microconvection in the interstitium that enhances penetration of anti-cancer drugs in the cancer cells.…”

Section: Introductionmentioning

confidence: 99%

Novel Drug Delivery Technique for Breast Cancer Therapy

Esenaliev¹

2002

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Section: Introductionmentioning

confidence: 99%