Causes of infantile autism: Some considerations from recent research

Rutter, Michael; Bartak, Lawrence

doi:10.1007/bf01537740

Cited by 142 publications

(35 citation statements)

References 14 publications

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“…An onset by the age of 30 months [38] is included as one of our diagnostic criteria. As in other centers evaluating autism the diagnosis is not made in the presence of electroencephalograms, audiometry, opthalmology, mucopolysaccharides, amino acid chromatography, or buccal smears that suggest another diagnostic entity.…”

Section: Subjects and Criteria For Selectionmentioning

confidence: 99%

Autism and attention: Theoretical considerations and a pilot study using set reaction time

Gold

1975

Child Psych Hum Dev

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We have presented an attentional model that may have value in the pathophysiology of autism. We have presented data that suggest attentional dysfunction and an attentional hypothesis that may explain autism's multisensory clinical appearance and natural history. Only further studies will be able to evaluate this hypothesis and hopefully provide us with something more promising to offer parent and child in the way of therapy.

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Section: Subjects and Criteria For Selectionmentioning

confidence: 99%

Autism and attention: Theoretical considerations and a pilot study using set reaction time

Gold

1975

Child Psych Hum Dev

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“…None of the subjects were being treated with psychotropic agents. The diagnosis of autism was made according to the diagnostic crite ria of Kanner [1943], Rutter [1968Rutter [ , 1972 and Rutter and Bartak [1971], with the E-2 score of Rimland [1965] as an adjunct.…”

Section: Methodsmentioning

confidence: 99%

Blood Serotonin and Free Tryptophan Concentration in Autistic Children

et al. 1984

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In 37 autistic children and 67 normal control subjects, determinations of plasma free and total tryptophan and blood serotonin levels were made simultaneously in order to establish a relationship between these parameters and the clinical rating scales: Children’s Psychiatric Rating Scale (CPRS-1), Werry-Weiss-Peters Activity Scale (WWPAS), and Developmental Quotient (DQ). The plasma free tryptophan level was significantly higher in autistic children than in normal control subjects. There tended to be a significant positive correlation between the plasma free tryptophan level and CPRS-1 or WWPAS score and a negative correlation between the plasma free tryptophan level and DQ. The blood serotonin level was significantly higher in autistic children than in normal control subjects. No correlation was established, however, between the blood serotonin level and CPRS-1, WWPAS score or DQ, and hence the clinical symptoms. Nor was there a correlation between blood serotonin and free tryptophan levels in these children. These results suggest that autistic children have some defect in tryptophan-serotonin metabolism in the brain, which is responsible for the clinical manifestations and behavioral abnormalities of infantile autism.

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“…A seminal study by Creak and Ini (1963) found no evidence of a parental personality stereotype as psychologically damaging and causal of autistic children. Further studies supported their work, finding no such personality type among mothers (Kolvin, Garside, & Kidd, 1971;Pitfield & Oppenheim, 1964;Rutter & Bartak, 1971). Rimland (1964), an American psychologist and a parent of a son with autism, refuted that he or his wife were 'refrigerator parents' and was one of the first to propose a biological basis for the disorder.…”

Section: Social Awareness and Service Provisionmentioning

confidence: 97%

Retracing the Historical Social Care Context of Autism: A Narrative Overview

D’Astous¹,

Manthorpe²,

Lowton³

et al. 2014

Br J Soc Work

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(2016) Retracing the historical social care context of autism: a narrative overview. The British Journal of Social Work, 46 (3). pp. [789][790][791][792][793][794][795][796][797][798][799][800][801][802][803][804][805][806][807] This version is available from Sussex Research Online: http://sro.sussex.ac.uk/54127/ This document is made available in accordance with publisher policies and may differ from the published version or from the version of record. If you wish to cite this item you are advised to consult the publisher's version. Please see the URL above for details on accessing the published version. Copyright and reuse:Sussex Research Online is a digital repository of the research output of the University.Copyright and all moral rights to the version of the paper presented here belong to the individual author(s) and/or other copyright owners. To the extent reasonable and practicable, the material made available in SRO has been checked for eligibility before being made available.Copies of full text items generally can be reproduced, displayed or performed and given to third parties in any format or medium for personal research or study, educational, or not-for-profit purposes without prior permission or charge, provided that the authors, title and full bibliographic details are credited, a hyperlink and/or URL is given for the original metadata page and the content is not changed in any way. The key themes from this narrative review suggest the interconnections between scientific development, social awareness and service provision for individuals with autism and their families and changes in social care over time.

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Causes of infantile autism: Some considerations from recent research

Cited by 142 publications

References 14 publications

Autism and attention: Theoretical considerations and a pilot study using set reaction time

Autism and attention: Theoretical considerations and a pilot study using set reaction time

Blood Serotonin and Free Tryptophan Concentration in Autistic Children

Retracing the Historical Social Care Context of Autism: A Narrative Overview

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