Causes of death in neonates born with a heart malformation

Šamánek, M; Goetzová, J; Benesová, D

doi:10.1016/0167-5273(86)90200-7

Cited by 17 publications

(9 citation statements)

References 7 publications

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“…When we supplemented this retrospective study with a prospective study in 1984 we ascertained that 39% of the children probably died for reasons unrelated to the heart and an additional 5% probably for reasons unrelated to the heart. In other words, 44% of neonates with heart defects who died probably did not die because of heart malformation [12].…”

Section: Discussionmentioning

confidence: 99%

Congenital Heart Disease Among 815,569 Children Born Between 1980 and 1990 and Their 15-Year Survival: A Prospective Bohemia Survival Study

1999

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The objective of this study was to ascertain the prevalence and survival rate of children born with a heart defect. A total of 816,569 children live-born between 1980 and 1990 in Bohemia (52,478 km 2 , population 6.314 million, western Czech Republic) were followed up and those with suspected heart disease referred to a center. Echocardiography was done in all of them. All dead children were autopsied. Congenital heart disease was found in 5030 of 816,569 children (6.16 per 1000 live births). The most frequent conditions were ventricular septal defect (41.59%), atrial septal defect (8.67%), aortic (7.77%) and pulmonary (5.81%) stenoses, transposition of the great arteries (5.39%), coarctation of the aorta (5.29%) and persistent ductus arteriosus (5.07%). The first week was survived by 92.46%, the first month by 89.14%, 6 months by 82.42%, and the first year of life by 80.02%, and 77.11% (95% CI 75.91-78.31%) survived to age 15 years. The best prognosis was found in pulmonary stenosis (15-year survival 95.55%), atrial septal defect (92.04%), persistent ductus arteriosus (90.59%), ventricular septal defect (89.37%) and aortic stenosis (88.39%). The worst results were attained in hypoplastic left heart, truncus arteriosus and pulmonary atresia with intact ventricular septum. In conclusion, the prevalence of congenital heart disease was 6.16 per 1000 live births; 77.11% of patients survived to age 15 years.

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Section: Discussionmentioning

confidence: 99%

Congenital Heart Disease Among 815,569 Children Born Between 1980 and 1990 and Their 15-Year Survival: A Prospective Bohemia Survival Study

1999

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“…A detailed clinical examination, ECG, echocardiography, CT and MRI and/or cardiac catheterisation with angiography proved or disproved heart disease in all cases with suspected CHD. There was a legal requirement for all children who died either at home or in a hospital (including those with unrecognised heart lesions) to undergo a postmortem examination 7 8. Isolated dextrocardia, non-stenotic bicuspid aortic or pulmonary valve and asymptomatic vascular abnormalities were not included.…”

Section: Methodsmentioning

confidence: 99%

Prenatal ultrasound screening of congenital heart disease in an unselected national population: a 21-year experience

Marek

Tomek

Škovránek

et al. 2010

Heart

184

134

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The nationwide prenatal ultrasound screening programme enabled detection of major cardiac abnormalities in 1/3 of patients born with any CHD and 80% of those with critical forms. Nevertheless, owing to the severity of lesions and associated extracardiac anomalies, the overall mortality of antenatally diagnosed CHD remains high. These findings are important for the understanding natural history of CHD for the establishing of screening programmes in Europe.

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“…A study from Bohemia found a noncardiac cause for death in all infants dying with Childhood outcomes of congenital heart defects 26 Perioperative death 61,63 Rarely: congestive heart failure; ASD, in 93% of infants dying with TOF, in 84% of infants dying with VSD and in 57% of infants dying with COA. 84 Most deaths from non-cardiac causes occurred on the first postnatal day. 84 Screening is unlikely to be beneficial in preventing deaths in this group of infants with extra-cardiac anomalies.…”

Section: Death During the First Year Of Life From Congenital Heart Dementioning

confidence: 99%

“…84 Most deaths from non-cardiac causes occurred on the first postnatal day. 84 Screening is unlikely to be beneficial in preventing deaths in this group of infants with extra-cardiac anomalies.…”

Section: Death During the First Year Of Life From Congenital Heart Dementioning

confidence: 99%

“…The congenital heart defect was considered directly responsible for death in 82% of infants with TGA, 79% of infants with HLH and 68% of infants with PA. 84 Infants with COA and TAPVC cases presenting in the newborn period are usually more severely affected and more likely to die in infancy. Repair of TOF can often be electively delayed until after 1 year of age, so deaths in infancy are likely to be related to earlier surgery or to severe defects.…”

Section: Death During the First Year Of Life From Congenital Heart Dementioning

confidence: 99%

See 1 more Smart Citation

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

Knowles¹,

Griebsch²,

Dezateux

et al. 2005

Health Technol Assess

213

143

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Causes of death in neonates born with a heart malformation

Cited by 17 publications

References 7 publications

Congenital Heart Disease Among 815,569 Children Born Between 1980 and 1990 and Their 15-Year Survival: A Prospective Bohemia Survival Study

Congenital Heart Disease Among 815,569 Children Born Between 1980 and 1990 and Their 15-Year Survival: A Prospective Bohemia Survival Study

Prenatal ultrasound screening of congenital heart disease in an unselected national population: a 21-year experience

Newborn screening for congenital heart defects: a systematic review and cost-effectiveness analysis

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