Cause of Neonatal Sepsis: Transplacental vs Environmental

Abstract

Objectives:To study the role of transplacental transmission and environmental factors in neonatal sepsis (0-3) days and incidence of early neonatal sepsis in obstetrics and gynecology wards of MGM Medical College Hospital. Materials and methods:The study was carried out on 100 full term women and their babies who delivered in MGM hospital. Their cord blood cultures were done. The nasal carrier state for Staphylococcus aureus (S. aureus) in all the health professionals working in labor room was also studied.Results: S. aureus was the most common organism grown in cord cultures of woman who delivered vaginally. None of the babies followed in wards showed any Sign of sepsis in first 72 hours. More than 50% of health professionals working in labor room were carriers of S. aureus. Conclusion:S. aureus is having environmental source and it causes late neonatal sepsis so none of the babies developed any Sign of sepsis in first 72 hours of life. Other organisms isolated probably responded to intrapartum antibiotics or maternal immunity played its role and so babies did not showed any s/o sepsis in first 3 days.