Causal relationships between the parameters of gas discharge visualization and leukocytogram

Background. From previous studies, it is known about the adaptogenic properties of Naftussya bioactive water and the Ukrainian phytocomposition "Balm Truskavets’". Both adaptogens have a common component of the composition - polyphenols, which suggests the existence of similar effects on the parameters of the body responsible for adaptation. The purpose of this study is to test the hypothesis. Material and methods. The object of clinical-physiological observation were 30 practically healthy individuals of both sexes with dysfunction of the neuro-endocrine-immune complex as a manifestation of maladaptation. Before and after a one-week course of using Balm (10 people) or Naftussya water (20 people), plasma levels of the main adaptation hormones, parameters of electroencephalogram (EEG), heart rate variability (HRV), phagocytosis, leukocytogram, as well as acupuncture and bioelectrophotonics were recorded. Results. 39 parameters (18 EEGs, 8 HRVs, 5 biophysical, 4 phagocytosis, as well as the Popovych’s leukocytary adaptation index, triiodothyronine, testosterone and cortisol) were identified, the physiologically favorable changes of which are common to both adaptogenic means. Conclusion. The influence of adaptogens of various nature on the state of adaptation of the body is non-specific and is implemented through the neuro-endocrine-immune complex.

Section: Fig 8 Average (M±se) Values Of Discriminant Root Before (B) ...mentioning

confidence: 88%

Similarity of adaptogenic effects of bioactive naftussya water and phytocomposition “Balm Truskavets’”

Popovych

2023

“…As the attitude to the GDV method is ambiguous, our laboratory conducted studies that proved its relevance [8,[10][11][12][13][15][16][17][18][19].…”

Section: Materials and Research Methodsmentioning

confidence: 99%

Effects of transcutaneous electrical stimulation with the device “VEB” ® on the human body

Babelyuk¹,

Babelyuk²,

Popovych

et al. 2022

Self Cite

Background. In 2015, a generator for electrotherapy and stimulation oh human nerve centers was created, called “VEB-1”®. Preliminary observation of volunteers revealed a modulating effect of a four-day course of electrical stimulation on the parameters of electroencephalogram, metabolism, as well as gas-discharge visualization (GDV). In this message, we present the results of the approbation of the device on an expanded contingent of volunteers with the use of additional research methods and a new modification of the device. Material and research methods. The object of observation were employees of the sanatorium “Moldova”, patients with chronic cholecystitis: 19 women 30-62 y and 19 men 25-63 y. In the morning registered HRV (“CardioLab+HRV”, “KhAI-Medica”, Kharkiv, UA), EEG (“NeuroCom Standard”, “KhAI-Medica”, Kharkiv, UA), kirlianogram by the method of GDV (“GDV Chamber”, “Biotechprogress”, SPb, RF), electroconductivity of skin in three pairs of points of acupuncture (“Medissa”), electrokinetic index of buccal epithelium ("Biotest", Kharkiv State University), as well as some endocrine, immune and metabolic parameters. After the initial testing, an transcutaneous electrical stimulation session was performed with a “VEB-1”® or a “VEB-2” devices. The next morning after completing the four-day course, retesting was performed. Results. Electrical stimulation causes a sympathotonic shift in the sympatho-vagal balance and an increase in PSD of delta-rhythm generating neurons combined with a decrease in PSD of beta- and theta-rhythm generating neurons. This is accompanied by increase in phagocytosis and favorable changes in immune, biochemical and biophysical parameters as well as increase in testosterone level in men only. The integral effects on the constellation of registered body parameters of both device modifications do not differ significantly. Conclusion. The "VEB" device exerts an adaptogenic effect on the body through transcutaneous electrical stimulation of neurons.

“…Finally, there is a further increase in the upper limit levels of activity of δ-rhythm generating neurons (cluster B+/A++). The described changes in parameters of EEG, HRV, hormones and biophotonics are negatively/positively correlated with the changes in parameters of phagocytosis [5,22,36,52] (as well as of immunity [4,6,8,22,35,37,38,51]), so effects of the Phytocomposition are physiologically favorable and therefore adaptogenic.…”

Section: Fig 3 the Clusters Of Normalized (Z±se) Parameters Before (B...mentioning

confidence: 99%

“…In conclusion, we will discuss the place and role of biophotonics and acupuncture parameters in the adaptogenic effects of the phytocomposition. Previously, it was shown in our laboratory that GDV parameters significantly correlate with parameters of the neuroendocrine-immune complex [3][4][5][6]8,9] and acupuncture points [7] and respond to the influence of another adaptogen -Naftussya bioactive water [23]. Unidirectional changes in the symmetry of the third and seventh Chakras, electrical conductivity of acupuncture points MC(AVL) (represent the immune system) and EEG alpha-rhythm as well as opposite changes in the delta-rhythm were found in this study.…”

Section: Fig 4 Individual and Average (M±se) Values Of Discriminant R...mentioning

confidence: 99%

The influence of the Ukrainian phytocomposition "Balm Truskavets'" on parameters of neuro-endocrine-immune complex and biophotonics in humans with maladaptation

Ruzhylo

Корда

et al. 2023

Background. Earlier we showed that the Ukrainian phytocomposition “Balm Truskavets’” exerts immediate modulating effects on parameters of EEG and HRV as well as biophotonics. In a pilot study on 10 volunteers, we found that the use of the phytocomposition for 11 days causes changes in EEGs parameters accompanied by a sympatho(adreno)mimetic effect. The modulating effects on the EEG&HRV parameters are combined with the changes in biophotonics parameters. This study was conducted on a four times larger cohort and with a wider range of methods. Materials and Methods. The object of observation were 16 women 46±15 ys and 24 men 50±11 ys. The volunteers were practically healthy, but the initial testing revealed deviations from the norm in a number of parameters of the neuro-endocrine-immune complex as a manifestation of maladaptation. The adaptation hormones levels, Popovych’s leukocytary adaptation and strain indices, parameters of phagocytosis, biophotonics, acupuncture points, EEG and HRV, before and after a 9-day course of use of phytocomposition registered. Results. A noticeable effect of the phytocomposition on 38 parameters was revealed, grouped into 6 clusters, of which 4 are enhancing and 2 are reducing. In particular, the reduced levels of the adaptation index and phagocytosis parameters increase significantly, instead, the increased levels of the strain index, testosterone, triiodothyronine, LF band HRV as well as two biophotonics parameters decrease, that is, there is a normalizing/beneficial effect. At the same time, normal levels of HRV-markers of vagal tone decrease, and cortisol and circulating catecholamines as well as the activity of β- and α-rhythm generating neurons increase, but within the normal range. Finally, there is a further increase in the upper limit levels of activity of δ-rhythm generating neurons. Conclusion. Ukrainian phytocomposition “Balm Truskavets’” exerts classical adaptogenic effects on parameters of neuro-endocrine-immune complex as well as biophotonics and acupuncture in humans with maladaptation.