Cationic Palladium(II) Catalysis: C−H Activation/Suzuki−Miyaura Couplings at Room Temperature

Abstract

Cationic palladium(II) catalyst realized facile C-H activation of aryl urea with arylboronic acids at room temperature. This reaction is extremely mild to carry out aromatic C-H activations through electrophilic substitution.

A Clean, Highly Efficient and One‐Pot Green Synthesis of Aryl/Alkyl/Heteroaryl‐Substituted Bis(6‐amino‐1,3‐dimethyluracil‐5‐yl)methanes in Water

“…Regardless of this, however, there are many examples of aqueous media reactions, [5] water used as a co-solvent or on-water [6] reactions performed without dissolving the organic compounds (coined as the "on-water-effect"). Efforts have been made to dissolve organic compounds in water by adding additives like surfactants [7] and applying heat.…”

Porous Single‐Crystalline Palladium Nanoparticles with High Catalytic Activities

“…When bromobenzene, which is less reactive than iodobenzene because of the larger CÀBr bond energy, is used, the TOF values of the 34-nm-sized Pd NP sample were 0.24 s À1 at 85 8C and 39.3 h À1 at room temperature. [29,30] There have been no reports with Pd nanostructures as the catalysts at room temperature. So far, the Suzuki coupling reactions at room temperature have been reported only with Pd complexes as the catalysts.…”

Recent advances in the application of group-10 transition metal based catalysts in C–H activation and functionalization

“…Liu et al [54] reported the synthesis of substituted dibenzofuran by phenol- Lipshutz et al [70] reported an unusual effect of cationic Pd in Suzuki-Miyaura reaction without using any metal oxidants or acid (Scheme 42). The authors found facile C-H activation of aromatic moiety followed by cross-couplings at room temperature.…”