2022
DOI: 10.3390/life12122007
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Categorization of the Aqueous Deficient Dry Eye by a Cut-Off Criterion of TMH Measured with Tearscope

Abstract: A decrease of the Tear Meniscus Height (TMH) has been proposed as a useful indicator for Aqueous Deficient Dry Eye (ADDE) categorization. The present study aimed to calculate a TMH cut-off criterion for the categorization or severity assessment of ADDE with the Tearscope. 200 participants with a previous Dry Eye Disease (DED) diagnosis according to TFOS DEWS-II criteria were recruited. TMH by slit-lamp illumination and Lipid Layer Pattern (LLP) with Tearscope were assessed to categorise the participants into t… Show more

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Cited by 9 publications
(5 citation statements)
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“…The sample size was calculated using PS Power and Sample Size Calculations Version 3.1.2 (Copyright© by William D. Dupont and Walton D. Plummer) based on the TFOS DEWS II Diagnostic Methodology report principles [7,13,14]. The literature-reported standard deviations (SDs) for symptomatology status (OSDI score), tear lm osmolarity, tear lm FBUT, and uorescein corneal staining were assumed to be 6.7, 4.8 mOsm/L, 2.9 s, and 2, respectively [7,11].…”
Section: Study Design and Calculationmentioning
confidence: 99%
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“…The sample size was calculated using PS Power and Sample Size Calculations Version 3.1.2 (Copyright© by William D. Dupont and Walton D. Plummer) based on the TFOS DEWS II Diagnostic Methodology report principles [7,13,14]. The literature-reported standard deviations (SDs) for symptomatology status (OSDI score), tear lm osmolarity, tear lm FBUT, and uorescein corneal staining were assumed to be 6.7, 4.8 mOsm/L, 2.9 s, and 2, respectively [7,11].…”
Section: Study Design and Calculationmentioning
confidence: 99%
“…A battery of clinical procedures was conducted in all participants according to the TFOS DEWS II Diagnostic Methodology report [7,13,14]. The tests were always performed in the same order, from the least to the most invasive, while the rst eye to be measured was randomly selected [7,13,14].…”
Section: Study Design and Diagnostic Criteriamentioning
confidence: 99%
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