2023
DOI: 10.1080/09273948.2023.2285449
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Capability of the Inter-Eye Differences in Osmolarity, Break-Up Time and Corneal Staining on the Diagnostic of Dry Eye

Hugo Pena-Verdeal,
Jacobo Garcia-Queiruga,
Belen Sabucedo-Villamarin
et al.
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Cited by 1 publication
(4 citation statements)
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“…This finding has direct implications for clinical practice, offering a quantitative and objective measure for diagnostic decision making. Interestingly, and contrary to other clinical tests that demonstrate larger differences between eyes in DED participants [31][32][33][34][35][36], the present analysis found that participants without ADDE could be differentiated from those with ADDE by showing greater inter-eye differences. It is important to note that ADDE participants showed generally lower TMH values, while No ADDE participants had higher values despite these inter-eye differences.…”
Section: Discussioncontrasting
confidence: 99%
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“…This finding has direct implications for clinical practice, offering a quantitative and objective measure for diagnostic decision making. Interestingly, and contrary to other clinical tests that demonstrate larger differences between eyes in DED participants [31][32][33][34][35][36], the present analysis found that participants without ADDE could be differentiated from those with ADDE by showing greater inter-eye differences. It is important to note that ADDE participants showed generally lower TMH values, while No ADDE participants had higher values despite these inter-eye differences.…”
Section: Discussioncontrasting
confidence: 99%
“…Other parameters, such as the osmolarity inter-eye variability, have been found to be useful for DED detection, suggesting that the higher osmolarity of the two eyes could be used in clinical practice because the lower value seems to reflect the transient effects of compensatory mechanisms however, some controversy has been found regarding this point in recent publications [35]. In addition to these results, a recent report supports the above idea, suggesting that not all diagnostic parameters suggested by the TFOS DEWS II Diagnostic Methodology report are candidates for a diagnosis based on inter-eye differences, emphasizing the need to explore each parameter individually in this regard [34].…”
Section: Discussionmentioning
confidence: 97%
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