Cataract Surgery and Intraocular Lens Implantation in Patients with Uveitis

Foster, C. Stephen; Fong, Lye Pheng; Singh, Gurinder

doi:10.1016/s0161-6420(89)32898-3

Cited by 184 publications

(68 citation statements)

References 7 publications

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“…The main outcome measure, the interval between the onset of uveitis and the first CE (U-CE interval), was examined in relation to clinical and ophthalmologic characteristics and treatment strategies before CE. 2 The risk of cataract formation in JIA-associated uveitis increases when posterior synechia are present at the initial examination and with treatment with a high dose of systemic corticosteroids. 3 Previously, the visual outcome of cataract surgery in JIA-associated uveitis was poor.…”

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Risk Factors for the Development of Cataract Requiring Surgery in Uveitis Associated with Juvenile Idiopathic Arthritis

Sijssens

Rothová

Vijver

et al. 2007

American Journal of Ophthalmology

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• PURPOSE: To identify the possible risk factors for the development of cataract requiring surgery in children with juvenile idiopathic arthritis (JIA)-associated uveitis.• DESIGN: Retrospective cohort study.• METHODS: Data of 53 children with JIA-associated uveitis, of whom 27 had undergone cataract extraction (CE), were obtained. The main outcome measure, the interval between the onset of uveitis and the first CE (U-CE interval), was examined in relation to clinical and ophthalmologic characteristics and treatment strategies before CE. 2 The risk of cataract formation in JIA-associated uveitis increases when posterior synechia are present at the initial examination and with treatment with a high dose of systemic corticosteroids. 3 Previously, the visual outcome of cataract surgery in JIA-associated uveitis was poor. Since new surgical techniques have been recommended, the results of cataract extraction (CE) have improved, but surgery in uveitic eyes of children still remains challenging. 4 The aim of our study was to evaluate which factors accelerate the development of cataract requiring surgery in JIA-associated uveitis. Therefore, clinical and ophthalmologic characteristics and the treatment strategies in children with JIA-associated uveitis were investigated in relation to the interval between the diagnosis of uveitis and the first cataract extraction (U-CE interval). METHODS WE REVIEWED THE MEDICAL RECORDS OF 53 CHILDRENwith JIA-associated uveitis (n ϭ 51) or antinuclear antibody (ANA)-positive uveitis without arthritis (n ϭ 2) diagnosed before the age of 16 years. These children represent all children with JIA-associated uveitis identified in a complete database search of the FC Donders

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“…2 The risk of cataract formation in JIA-associated uveitis increases when posterior synechia are present at the initial examination and with treatment with a high dose of systemic corticosteroids. 3 Previously, the visual outcome of cataract surgery in JIA-associated uveitis was poor.…”

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confidence: 99%

Risk Factors for the Development of Cataract Requiring Surgery in Uveitis Associated with Juvenile Idiopathic Arthritis

Sijssens

Rothová

Vijver

et al. 2007

American Journal of Ophthalmology

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“…Many published series have reported excellent visual results after extracapsular cataract extraction with a rigid one-piece IOL, [1][2][3] as well as phakoemulsification using a foldable IOL. 4,5 This has been because of a combination of an improvement in microsurgical techniques including small incision surgery, the appropriate timing of the surgery, and adequate pre-, periand postoperative control of the intraocular inflammation.…”

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Brown deposits in the optic of foldable intraocular lenses in patients with uveitis

Manuchehri

Mohamed

Cheung

et al. 2004

Eye

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Purpose To report a new finding of brown deposits scattered in the substance of the optic of foldable intraocular lenses (IOL) following phakoemulsification in patients with uveitis. Methods Consecutive uveitis patients (54 patients, 71 eyes) who had undergone phakoemulsification with a foldable posterior chamber IOL between March 1996 and November 2000 were studied. A variety of biomaterials from seven different manufacturers had been implanted. One masked observer using slit-lamp biomicroscopy assessed deposits in the substance of the optic of the IOL. Results Brown deposits were detected in the substance of the optic of 25/71 (35%) IOLs with 18/22 (82%) of AcrySof MA60BM IOLs being affected. Using logistic regression analysis, the AcrySof MA60BM IOL was significantly associated with the presence of deposits (adjusted odds ratio ¼ 38.5, 95% CI 6.9-200, Po0.001). Using multiple regression analysis, there was a significant association between the severity of deposits and the use of the AcrySof MA60BM IOL (P ¼ 0.005). Compared with other foldable IOLs implanted, the AcrySof MA60BM IOL was 38.5 times more likely to develop intra-IOL deposits. There was no association with those eyes that had undergone increased intraocular manipulations. The deposits did not appear to affect visual acuity. Conclusions To our knowledge the finding of brown intra-IOL deposits has not previously been described. These deposits are more frequent in the AcrySof MA60BM implant than the other foldable implants studied. They share some similarities with glistenings, but their exact nature remains unknown.

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“…Cataract extraction in the patients with chronic uveitis may cause an inflammation which is more intensive and difficult to control than the non-uveitic eyes. Developments in the cataract surgery and treatment of uveitis with antiinflammatory, cytotoxic, and immunomodulatory agents, preceded extracapsular cataract extraction (ECCE) and intraocular lens (IOL) implantation in uveitic eyes with complicated cataracts (Foster et al 1989;Brinkman et al 1990;Chung & Yeh 1990). However, a few studies have been reported about extracapsular cataract extraction (ECCE) and intraocular lens (IOL) implantation in Behçet's disease (Ciftci & Ozdemir 1996;Tabbara & Chavis 1997).…”

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The results of cataract extraction and intraocular lens implantation in patients with Behçet's disease

Süllü

Öge

Erkan

2000

Acta Ophthalmologica Scandinavica

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Cataract Surgery and Intraocular Lens Implantation in Patients with Uveitis

Cited by 184 publications

References 7 publications

Risk Factors for the Development of Cataract Requiring Surgery in Uveitis Associated with Juvenile Idiopathic Arthritis

Risk Factors for the Development of Cataract Requiring Surgery in Uveitis Associated with Juvenile Idiopathic Arthritis

Brown deposits in the optic of foldable intraocular lenses in patients with uveitis

The results of cataract extraction and intraocular lens implantation in patients with Behçet's disease

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